Connecting European Neuroscience

Elisabeth Binder

Ordinary member, Programme Committee FENS Forum 2016

Curriculum Vitae

Education:

1989 – 1995         MD: Medical School University of Vienna, Austria

1992 - 1994          Exchange scholarship from the European Community (ERASMUS Scholarship) at the Université Libre de Brussels, Belgium

08-1995 to 01-2000    PhD: PhD program in Neuroscience at the Emory University, Atlanta, Georgia USA

02-2000 to 08-2004    Clinical training in Psychiatry and post-doctoral work in Human Genetics at the Max Planck Institute of Psychiatry in Munich, Germany

 

Professional and academic career

09-2004 to 8-2011    Assistant Professor at Emory University School of Medicine; Department of Psychiatry and Behavioral Sciences

06-2007 to 7-2013    Research Group Leader at Max-Planck Institute of Psychiatry (Research Group: Molecular Genetics of Depression), W2-equivalent position (Joint appointment with Emory University School of Medicine)

Starting 09-2011       Associate Professor at Emory University School of Medicine; Department of Psychiatry and Behavioral Science

Starting 08-2013       Director, Dept. of Translational Research in Psychiatry, Max-Planck Institute of Psychiatry

 

Honours and awards

2006   National Alliance for Research on Schizophrenia and Depression (NARSAD) Young Investigator Award

2006   Rafaelson Young Investigator Award; Collegium Internationale Neuropsychopharmacologicum (CINP)

2007   Doris Duke Clinical Scientist Development Award

2007   2007 NARSAD Michael F. Kaplan Investigator

2008   Hormosan-Pharma Research Award

2009   Behrens-Weise-Stiftung grant

2010   Theodore Reich Young Investigator Award of the International Society of Psychiatric Genetics

2012   Max Hamilton Memorial Prize of the Collegium Internationale Neuropsychopharmacologicum (CINP)

 

General administrative and organisational experience

Scientific services:

-  External advisory board member of the Post Traumatic Stress Disorder and Traumatic Brain Injury Clinical Consortium sponsored by the US Department of Defense since 2009.

-  Deputy director of the Committee for Neurobiology and Genetics of the German Society for Psychiatry and Psychotherapy since 2008

-  Member of the Awards Committee of the International Society of Psychiatric Genetics (ISPG) (2013-2015)

-  Member of the Advisory Committee of the Child & Brain Development Program of the The Canadian Institute for Advanced Research (2014-)

-  Member, Executive Committee ECNP 2014-2017

 

Conference organization:

- Member of the Scientific Committee of the focused conference session: New Approaches and Targets in Psychiatry. WorldPharma 2010, Copenhagen

- 2011 World Congress of Psychiatric Genetics, Washington D.C., Program Committee member 

- 2012 World Congress of Psychiatric Genetics, Hamburg, Local Organizing Committee member 

- 2013 World Congress of Psychiatric Genetics, Boston, Program Committee member

- Member of the International Scientific Committee (ISC) of the CINP Thematic Meeting on Pharmacogenomics and Personalised Medicine in Psychiatry (Tel Aviv 2013)

- Member of the Society of Biological Psychiatry's Program Planning Committee for the 2013 through 2015 meetings

-  Member of the Scientific Programme Committee for the 28th ECNP Congress 2015

 

Editorial Boards:

-  Frontiers in Molecular Psychiatry: Review Editor since 2010

-  Biology of Mood and Anxiety Disorders: Associate Editor since 2010

-  Current Psychiatry: Section editor: – Section: Genetics

-  Genes, Brain and Behavior: Member Editorial Board since 2012

-  Journal of Neural Transmission: Field editor since 2012

-  Neurobiology of Stress: Member Editorial Board since 2014

 

Research interests

Molecular basis of mood and anxiety disorders with a focus on stress response and early adverse experience

Methods:  genome-wide association studies and gene expression studies, genome-wide DNA methylation experiments and next generation sequencing, gene x environment interaction

 

Selected Publications

  • Mehta D, Klengel T, Conneely KN, Smith AK, Altmann A, Pace TW, Rex-Haffner M, Loeschner A, Gonik M, Mercer KB, Bradley B, Müller-Myhsok B, Ressler KJ, Binder EB. Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proc Natl Acad Sci U S A. 2013 May 14;110(20):8302-7.
  • Klengel T, Mehta D, Anacker C, Rex-Haffner M, Pruessner JC, Pariante CM, Pace TWW, Mercer KB, Mayberg HS, Bradley B, Nemeroff CB, Holsboer F, Heim CM, Ressler KJ, Rein T, Binder EB. Allele-specific DNA demethylation in FKBP5: a molecular mediator of gene x childhood trauma interactions. Nature Neuroscience 2013 Jan;16(1):33-41. doi: 10.1038/nn.3275
  • Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Using Polymorphisms in FKBP5 to Define Biologically Distinct Subtypes of Posttraumatic  Stress Disorder: Evidence From Endocrine and Gene Expression Studies. Arch Gen Psychiatry. 2011 Sep;68(9):901-10. Epub 2011 May 2.
  • Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 2011 Apr 28;70(2):252-65
  • Binder EB, Bradley RG, Liu W, Epsetein MP, Deveau TC, Mercer KB, Tang Y, Gillespie CF, Heim CM, Nemeroff CB, Cubells JF, Ressler KJ. Association of FKBP5 Polymorphisms and Childhood Abuse with Risk of Posttraumatic Stress Disorder Symptoms in Adults, JAMA 2008;299(11):1-5.
  • Bradley RG, Binder EB, Epstein MP, Tang Y, Nair HP, Liu W, Gillespie CF, Berg T, Evces M, Newport DJ, Stowe ZN, Heim CM, Nemeroff CB, Schwartz A, Cubells JF, Ressler KJ. Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene. Arch Gen Psychiatry. 2008 Feb;65(2):190-200.

Elisabeth Binder

Max Planck Institute of Psychiatry,
Director, Department of Translational Research
Kraepelinstr. 2, 80804 Munich
Phone: + 49 89 306 22 586
Fax: + 49 89 306 22 370
E-mail:ebinder@emory.edu

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