Professional and academic career
1988 MD degree, University of Alicante, Spain
1992 PhD in Neuroscience, University of Alicante Spain
Postdoctoral Fellow, Biophysics and Neurobiology labs, Rockefeller University, New York, USA
Postdoctoral Fellow/Associate, Dr. McCormick’s lab, Yale University, New Haven, USA
Investigator/Physiology Professor, Insitute Neuroscience Alicante, Spain
ICREA Research Professor at IDIBAPS (Institute Biomedical Research Albert Pi i Sunyer), Barcelona, Spain
Honours and awards
1993-1994 Postdoctoral Award, Formación Personal Investigador, Ministry of Education
1995 NATO postdoctoral award
1996 American Epilepsy Foundation Postdoctoral Award (1996)
2001 Human Frontiers Science Foundation Program Grant
Administrative and organisational experience
2001 and 2004
Co-director of international Summer Neuroscience Course Duques de Soria Foundation, Spain
Member of EDAB (European Dana Alliance for the Brain)
Member of the Research Grant Review Committee. Human Frontier Science Program.
2012 and 2015
Organizer of international B-Debate workshops
Specialty Chief Editor, Frontiers in Systems Neuroscience
President of the Program Committee, Spanish Society of Neuroscience
Neuronal connectivity and cellular and synaptic properties shape emergent activity generated by neuronal networks. Such activity has then effects upon the network, regulating mechanisms like membrane properties and synaptic plasticity. We are interested in different aspects of network activity: its patterns, how it is generated, its regulating mechanisms, the information it encodes, and the consequences of this activity upon the network. To understand the impact that different processes have upon the resultant network activity is critical to combine the experiments with the use of computational models. We also find emergent cortical rhythms highly useful to identify functional alterations in the brain of transgenic models of neurological disorders and to explore their potential reversion. Lastly, the integration of cortical information that gives rise to body representation and the combination of brain-computer interfaces and virtual reality for understanding these processes.
- Gain modulation of synaptic inputs by network state in auditory cortex in vivo, Reig, R., Zerlaut, Y., Vergara, R., Destexhe, A. and Sanchez-Vives, MV. The Journal of Neuroscience (in press, 2015).
- Abolafia, J. M., Vergara, R., Arnold, M. M., Reig, R., & Sanchez-Vives, M. V. (2010). Cortical auditory adaptation in the awake rat and the role of potassium currents. Cerebral Cortex, bhq163.
- Sanchez-Vives, M. V., Mattia, M., Compte, A., Perez-Zabalza, M., Winograd, M., Descalzo, V. F., & Reig, R. (2010). Inhibitory modulation of cortical up states. Journal of Neurophysiology, 104(3), 1314-1324.
- Compte, A., Reig, R., Descalzo, V. F., Harvey, M. A., Puccini, G. D., & Sanchez-Vives, M. V. (2008). Spontaneous high-frequency (10–80 Hz) oscillations during up states in the cerebral cortex in vitro. The Journal of Neuroscience, 28(51), 13828-13844.
- Winograd, M., Destexhe, A., & Sanchez-Vives, M. V. (2008). Hyperpolarization-activated graded persistent activity in the prefrontal cortex. Proceedings of the National Academy of Sciences, 105(20), 7298-7303.
- Slater, M., Perez-Marcos, D., Ehrsson, H. H., & Sanchez-Vives, M. V. (2008). Towards a digital body: the virtual arm illusion. Frontiers in Human Neuroscience,2.
- Reig, R., Gallego, R., Nowak, L. G., & Sanchez-Vives, M. V. (2006). Impact of cortical network activity on short-term synaptic depression. Cerebral Cortex,16(5), 688-695.
- Sanchez-Vives, M. V., & Slater, M. (2005). From presence to consciousness through virtual reality. Nature Reviews Neuroscience, 6(4), 332-339.
- Sanchez-Vives, M. V., & McCormick, D. A. (2000). Cellular and network mechanisms of rhythmic recurrent activity in neocortex. Nature Neuroscience,3(10), 1027-1034.
- Kim, U., Sanchez-Vives, M. V., & McCormick, D. A. (1997). Functional dynamics of GABAergic inhibition in the thalamus. Science, 278(5335), 130-134.