Connecting European Neuroscience

Schuman, Erin

Member, The Brain Conferences Committee (2014 - present)
Member, Programme Committee for the FENS Forum (2012 - 2018)

Curriculum Vitae

Professional and academic career

2009-present
Director, Max Planck Institute for Brain Research, Frankfurt, Germany
2004-2010
Professor, Caltech, Biology
2004-2009
Investigator, HHMI
2007-2009
Option Representative, Division of Biology, Caltech
2008
INSERM-sponsored visiting Faculty, Ecole Normale Superieure, Paris
2005
Visitor in Biology, Russ Fernald’s lab, Stanford University
2002-2004
Associate Investigator, Howard Hughes Medical Institute
2000-2006
Executive Officer in Biology, Caltech
1999-2004
Associate Professor, Caltech, Biology
1997-2002
Assistant Investigator, Howard Hughes Medical Institute
1993-1999
Assistant Professor, Caltech, Biology
1990-1993
Postdoctoral Fellow, Stanford University, PI: Daniel V. Madison
1990
Postdoctoral fellow, Princeton University, PI: Gregory Clark
1985-1990
Graduate student, Princeton University, PI: Joseph Farley and Gregory Clark

Honours and awards

1994-1996
Alfred P. Sloan Research Fellow
1994-1998
John Merck Scholar
1995-1999
Pew Biomedical Scholar
1995
American Association of University Women Emerging Scholar
1996-1998
Beckman Young Investigator Award
1997
Howard Hughes Medical Institute Assistant Investigator
2002
Howard Hughes Medical Institute Associate Investigator
2005
Howard Hughes Medical Institute Investigator
2013
Hodgkin-Huxley-Katz Prize Lecture for 2013
2013
Alexander Cruickshank Lecture, Gordon Research Conference

Administrative and organisational experience

2012-
FENS Forum (2014) Program Committee
2012-
Society for Neuroscience Axelrod Prize Committee
2011
Co-Chair, Gordon Conference on Dendrites
2011-
Editorial Board of Learning & Memory
2011-
Panel Member, ERC Starting Grant
2010-
Scientific Advisory Board, Neuroscience Institute, Helsinki
2010-
Society for Neuroscience International Affairs Committee
2010-
Wellcome Trust Core Interview Panel
2009
Co-Organizer, Cell-adhesion symposium, Cell Biology meeting
2009
Organizer, JFRC Protein Translation at the Synapse
2008-
Kavli Neuroscience Center Advisory Board
2008
Advisory Committee, Harvard University, Molecular-Cellular Biology
2004-2007
NIH Study section member, NIH, MDCN I and SYN
2007
Organizer, JFRC Protein Translation at the Synapse
2003
Co-Chair, Cold Spring Harbor Meeting on Learning and Memory
2001
Chair, Gordon Conference on Neural Plasticity
2001
Co-Organizer, Keystone Meeting on the Hippocampus and Synapses
1998
Co-Chair, Gordon Conference on Neural Plasticity
1996-1998
Co-Director, Brain Development and Function Course, CSHL
1995
Faculty, Neural Systems and Behavior, Marine Biological Laboratory

Research interests

My research activities focus on synapses, the points of contact and communication between neurons. The ability of synapses to change throughout the lifetime of the animal contributes to the ability to learn and remember. We are interested in how synapses are modified at the cellular and molecular level. We are also interested in how neuronal circuits change when synapses change their properties. We conduct all of our studies in the hippocampus, a structure known to be important for memory in both humans and animals. We use molecular biology, electrophysiology and imaging in our research, with the following major areas: local protein synthesis and degradation, transcriptomics and proteomics, cell biology of synaptic transmission.

Selected Publications

  • Cajigas IJ, Tushev G, Will TJ, tom Dieck S, Fuerst N, and Schuman EM (2012) The local transcriptome in the synaptic neuropil revealed by deep sequencing and high-resolution imaging. Neuron, 74: 453-466
  • Rutishauser U, Ross IB, Mamelak AN, and Schuman EM (2010) Human memory strength is predicted by theta-frequency phase-locking of single neurons. Nature 464: 903-907
  • Dieterich DC, Hodas, JJL, Gouzer G, Shadrin IY, Ngo JT, Triller A, Tirrell DA, and Schuman EM (2010) In situ visualization and dynamics of newly synthesized proteins in rat hippocampal neurons. Nature Neurosci., 13: 897-905
  • Taylor AM, Dieterich DC, Cho J, Ito H, Kim SA, and Schuman EM (2010) Microfluidic local perfusion chambers for the visualization and manipulation of synapses. Neuron, 66: 57-68
  • Bingol B and Schuman EM (2006) Activity-dependent dynamics and sequestration of proteasomes in dendritic spines. Nature, 441: 1144-1148
  • Dieterich DN, Link AJ, Graumann J, Tirrell DT and Schuman EM (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal non-canonical amino acid tagging (BONCAT). Proc. Natl. Acad. Sci., 103: 9482-9487
  • Sutton MA, Ito, H, Cressy P, Kempf C, Woo, J and Schuman EM (2006) Miniature neurotransmission stabilizes synaptic function via tonic suppression of local dendritic protein synthesis. Cell, 125: 785-799
  • Remondes M and Schuman EM (2004) Role for a cortical input to hippocampal area CA1 in the consolidation of a long-term memory. Nature, 431: 699-703
  • Sutton MA, Aakalu GN, Wall N, and Schuman EM (2004) Regulation of dendritic protein synthesis by miniature synaptic events. Science, 304: 1979-1983
  • Remondes AM and Schuman EM (2002) Direct cortical input modulates plasticity and spiking in CA1 pyramidal neurons. Nature, 416: 736-740

Prof. Dr. Schuman, Erin

Max Planck Institute for Brain Research
Department of Synaptic Plasticity
Max-von-Laue-Str. 4
60438 Frankfurt/Main
Germany

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