Connecting European Neuroscience

Advanced Techniques for Synapse Biology course directors

Matthijs Verhage received post-doctoral training at the labs of David Nicholls (Dundee, UK) and the recent Nobel laureate Thomas C. Südhof (HHMI, Dallas, USA). Since 2000 he is full professor and head of the Department of Functional Genomics at the Vrije Universiteit (VU) and VU University Medical Center (VUmc) in Amsterdam. Matthijs Verhage is partner of several European research consortia (EU-Synapse, EuroSpin, SynSys), member of national and international grant committees, editorial boards and governmental advisory boards. He is also consultant/scientific advisor for Life Science companies in The Netherlands, Spain, Switzerland and Japan. In 2001 he was the Pionier/VICI laureate of the Dutch Organization for Scientific Research (NWO). In 2012 he received the ERC Advanced Grant of the European Research Council.

10 key papers of the last 5 years:

  • - Aarts et al (2014) Nature Neurosci. 17, p491-6.
  • - Cijsouw et al. (2014) J. Cell Biol. 204, p759-75.
  • - Li et al. (2013) Neuron 79, p970-86.
  • - Ripke et al. (2013) Nature Genet. 45, p1150-9.
  • - Van der Sluis et al. (2013) Mol. Psychiatry 18, p2-13.
  • - Heutink and Verhage (2012) Neuron 75, p935-8.
  • - Groffen et al. (2010) Science 327, p1614-8.
  • - Mohrmann et al. (2010) Science 330, p502-5
  • - de Wit et al. (2009) Cell 138, p935-46.
  • - Gerber et al. (2008) Science 321, p1507-10.
  • On-site chairs:
  •     Laurent Groc, University of Bordeaux, France

  • Laurent Groc identified a form of glutamate receptor plasticity in immature synapses as a post-doc with Eric Hanse (Goteborg, Sweden). Laurent then explored glutamate receptor trafficking in developing neurons using single molecule tracking and electro-physiology. He currently heads a lab at the Interdisciplinary Institute for Neuroscience in Bordeaux, focusing on receptor dynamics in developing networks. He will instruct single nanoparticle tracking of membrane receptors in developing neurons. 
  • Nathalie Sans, University of Bordeaux, France 
    • Natalie Sans was a post-doc with Robert J. Wenthold at NIH in Bethesda (USA). She identified several novel components involved in intracellular trafficking of AMPA and NMDA receptors and studies the influence of their traffic on the structure and function of glutamatergic synapses. She is currently an INSERM Research Director at the Neurocentre Magendie at the University of Bordeaux, France. She continues to study intracellular traffic in relation with spine structure and function and develop new projects relying on multidisciplinary approaches to identify and define the specific function of planar cell polarity signaling in neuronal polarity and the impact of the disruption of this signaling in pathological context. Nathalie will instruct synapse biochemistry and postsynaptic trafficking studies in cultured neurons.

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