In collaboration with FENS and Wiley-Blackwell, EJN is proud to announce that the winner of the "Best Publication Award 2013" is Dr. Lisa Schnell,
researcher at the Brain Research Institute of the University and ETH of Zurich, Switzerland.
She receives this Award for her first-authored publication in EJN:
"Combined delivery of Nogo-A antibody, Neurotrophin-3 and NMDA-NR2D subunits establishes
a functional detour in the hemisected spinal cord."
(published in the European Journal of Neuroscience, Volume 34, Issue 8, pages 1256–1267, October 2011)
The main focus of Dr. Schnell's work is to understand the complex neuronal and molecular events that follow injury of the spinal cord. Despite early
regenerative processes, functional healing of the damaged tissue does not occur. The discovery of the growth-inhibitory myelin component Nogo-A in the
laboratory of Dr. Martin E. Schwab, and its subsequent neutralization with an antibody in vivo, has been a major turning point in the field of spinal
cord injury. Their demonstration of long-distance regeneration of axons has had a tremendous impact on the scientific community and drew many researchers
into this fascinating area. In the EJN research report that was selected as the winner of the Best Publication Award 2013, the authors have conducted
anatomical tracing, electrophysiology and behavioral experiments and found that, in adult rats, the combined treatment of anti-Nogo-A antibody,
neurotrophin NT-3 and NR2d subunits of NMDA receptors induced the appearance of a functional “detour” around the lesion and improved recovery of
function after spinal cord injury in adult rats. This novel combination treatment holds great promise to help improve the function of the damaged
Dr. Schnell's research for the benefit of paraplegic patients was supported by the Christopher and Dana Reeve Foundation.
Dr. Schnell will receive this award of £3,000 at the upcoming FENS Featured Regional Meeting in Prague, September 11-14, 2013. She will give a Special Lecture at this meeting.
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