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.: Kaczmarek, Leszek

Programme Committee Member

Prof. Leszek Kaczmarek
Nencki Institute
3, Pasteur Str.
02-093 Warsaw, Poland
Phone: +(48) 22 650 3001
Fax: +(48) 22 822 5342
E-mail: L.Kaczmarek@nencki.gov.pl
Homepage: http://neurogene.nencki.gov.pl

Personal

born 1957, Poland

Professor at the Department of Molecular and Cellular Neurobiology Nencki Institute, Warsaw, Poland (http://neurogene.nencki.gov.pl) and Chair, Division of Biological Sciences, Polish Academy of Sciences

Curriculum Vitae

Previous selected appointments and affiliations

2001-2002
Visiting Senior Fulbright Scholar, Department of Neurobiology, University of California, Los Angeles, USA
1994-1996, 1998
Visiting Professor, Department of Psychology, McGill University, Montreal Quebec, Canada.
1987,1988,1990, 1992
Contract Professor, University of Catania, Italy.
1984-1986
Postdoctoral fellow, Temple University, Philadelphia, USA (lab of Dr. R. Baserga)

Major Honors and Awards

2004
Member of European Dana Alliance for the Brain (EDAB)
2001
Member of Academia Europea
2000
FNP (Foundation for Polish Science) Prize 2000
2000
Member of EMBO (European Molecular Biology Organization)
1998
Corresponding member of the Polish Academy of Sciences
1998
Polonia Restituta (by the President of the Republic of Poland)

Participation in International Professional Organizations

2006-now
European Research Council: Member of the Neuroscience Panel
2006-now
Academia Europaea: Member of the Physiology Section
2003-now
EMBO: member of the Fellowship Committee
2003-2005
International Brain Research Organization, IBRO: Member of the Executive Committee and chair, Central and Eastern Europe Regional Committee
1995-1999
International Society for Neurochemistry, ISN: Member of the Council

Additional information

20 promoted PhDs
More than 130 original scientific publications
Principal investigator on more than 30 national and international research grants
Invited lecturer at more than 80 international and national meetings and congresses
Member of the Program Committees: ISN Berlin '99, FENS Lisboa '04, FEBS Warsaw '04, ISN Innsbruck '05

Major research achievements

Discovery of c-Myc role in regulation of the cell cycle
Discovery of the learning-related gene expression in the mammalian brain
Revealing apoptotic component of excitotoxicity in the adult brain
Discovery of specific role of cyclin D2 in the adult brain neurogenesis
Discovery of involvement of matrix metalloproteinaes in neuronal plasticity

Selected Publications

  • Szklarczyk A., Lapinska J., Rylski M., McKay R.D.G., Kaczmarek L. Matrix metalloproteinase -9 undergoes expression and activation during dendritic remodeling in adult hippocampus. J. Neurosci., 22: 920-930, 2002.
  • Kaczmarek L., Lapinska-Dzwonek J., Szymczak S., Matrix metalloproteinases in the adult brain physiology: a link between c-Fos, AP-1 and remodeling of neuronal connections? EMBO J., 21: 6643-6648, 2002.
  • Jaworski J., Mioduszewska B., Sanchez-Capelo A., Figiel I., Habas A. Gozdz A., Proszynski T. Hetman M., Mallet J., Kaczmarek L. Inducible cAMP Early Repressor, an endogenous antagonist of cAMP Responsive Element-Binding Protein, evokes neuronal apoptosis in vitro. J. Neurosci, 23: 4519-4526, 2003.
  • Frankland P.W., Bontempi B., Talton L.E., Kaczmarek L., Silva A.J. The involvement of the anterior cingulate cortex in remote contextual fear memory. Science, 304: 881-883, 2004.
  • Kowalczyk A., Filipkowski RK, Rylski M., Wilczynski G.M., Konopacki F.A., Jaworski J., Ciemerych M.A., Sicinski P., Kaczmarek L. The critical role of cyclin D2 in adult neurogenesis. J. Cell Biol., 167: 209-213, 2004.
  • Nagy, V., Bozdagi, O., Matynia, A., Balcerzyk, M., Okulski, P., Dzwonek, J., Costa, R.M., Silva, A.J., Kaczmarek, L., Huntley, G.W. Matrix metalloproteinase (MMP-9) is required for hippocampal late-phase LTP and memory. J. Neurosci., 26: 1923-1934, 2006.
  • Knapska E., Nikolaev E., Boguszewski P., Walasek G., Blaszczyk J., Kaczmarek L., Werka T. Between-subject transfer of emotional information evokes specific pattern of amygdala activation. Proc. Natl. Acad. Sci. USA, 103: 3858-3862, 2006.