Connecting European Neuroscience

Understanding and targeting Alzheimer's disease (2019)

5-8 May 2019: Rungstedgaard, north of Copenhagen, Denmark

Dementia poses one of the largest health and economic problems in the world with over 50 million people worldwide living with dementia, no disease modifying treatments available, and numbers set to dramatically increase as our population ages. Neuroscience research has the real potential to change this bleak future and develop effective ways to prevent or treat the diseases that cause dementia.

MicroThree of our current grand challenges towards this goal are to understand why certain brain regions are susceptible to the accumulation of pathology and neurodegeneration early in Alzheimer’s disease and related dementias, how pathologies then spread from these vulnerable regions to damage the rest of the brain, and finally how risk factors like ApoE modulate disease progression.

In this meeting, we will address the best way to move forward as a field in addressing these knowledge gaps with an emphasis on the emerging data in the field implicating non-neuronal contributors to disease risk and regional vulnerability.  The latest clinical trials and the requirement of biomarkers for early risk assessment will be discussed on the background of our understanding of disease mechanisms.  The meeting will end with a podiums discussion on the pros and cons of the amyloid cascade hypothesis.

  Photo description: Microglia P2Y12 adult cortex, Photo credits: Lasse Dissing-Olesen, Stevens Lab


          CHaass   BethS
  Christian Haass   Beth Stevens
  LMU Munich & German Center for Neurodegenerative Diseases, Germany   Harvard Medical School, USA


Venue: Rungstedgaard, Denmark  

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The Brain Conferences

The Brain Conferences are intimate-scale meetings focused on current topics in neuroscience. Two conferences per year are organised by FENS in collaboration with Lundbeck Foundation, the awarder of The Brain Prize.