Connecting European Neuroscience

Ph.D. Student in Brighton/UK

27 February 2018

Ph.D. Student in Brighton/UK

Job ID
15270
Place
Brighton/UK

Description

Encoding of information at the first synapse of the visual system

as part of a Doctoral training programme:

http://www.sussex.ac.uk/internal/doctoralschool/funding/sussexleverhulme

one project is available between the labs of Tom Baden (www.badenlab.org) and Leon Lagnado (http://www.sussex.ac.uk/profiles/179337):

Visual processing in the retina depends on the transformation of signals as they are transmitted across synapses (Lagnado & Schmitz, Annu Rev Vis Sci. 2015; Franke et al., Nature. 2017 542, 439-44). The first synapses in the visual pathway are structurally distinct and employ a “vesicle code” that represents information by both the rate and, surprisingly, the amplitude of events releasing neurotransmitter. We will investigate this code at photoreceptor synapses using multiphoton imaging in the retina of transgenic zebrafish. How does the vesicle code transmit information from cones of different colour? How is it adapted to cones sampling different parts of visual space? How does it compare to synapses transmitting the visual signal in the inner retina? The project involves both experiments and computer-based analysis. Students should have a background in neuroscience, engineering, physics or computing.

Job Information

Closing date:
2018-03-05
Contract length:
42 months
Institution:
University of Sussex
Department:
Sussex Neuroscience

Contact Information

Tom Baden
School of Life Sciences
University of Sussex
BN1 9QG
Brighton, UK
Phone
+44 1273 873772
Email
t.baden@sussex.ac.uk
Website
http://www.badenlab.org

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