Connecting European Neuroscience

Post-doctoral position in New York/USA

03 March 2018

Post-doctoral position in New York/USA

Job ID
15306
Place
New York/USA

Description

Postdoctoral positions are available immediately for highly motivated individuals with an interest in molecular mechanisms underlying synaptic transmission in the lab of Dr. Jeremy Dittman at Weill Cornell Medical College in New York City. The Dittman lab utilizes cutting-edge molecular and genetic techniques together with quantitative imaging, biochemical and electrophysiological approaches to probe the molecular machinery controlling neurotransmitter release.

Projects examine several critical presynaptic molecules such as complexin, Munc13, and Munc18, as well as GPCR signaling at the synapse. Our lab uses C. elegans as a model in vivo system together with in vitro biochemical and computational approaches. We also benefit from a highly collaborative local environment with excellent labs in our department including expertise in synaptic and single-molecule imaging in cell culture, NMR spectroscopy, and lipid biochemistry. Weill Cornell is part of a vibrant tri-institutional research community including Rockefeller University and Memorial Sloan Kettering Cancer Center in the heart of New York City.
Current projects focus on mechanisms by which complexin and Munc13 control synaptic vesicle fusion as represented by:
Wragg, RT, Snead D, Dong Y, Ramlall TF, Menon I, Bai J, Eliezer D, Dittman JS. Synaptic vesicles position complexin to block spontaneous fusion. Neuron 2013 77(2):323-334.

Michelassi, FE, Liu H, Hu Z, Dittman JS. A C1-C2 module in Munc13 inhibits calcium-dependent neurotransmitter release. Neuron 2017 95(3):577-590.

Candidates should have a PhD and should have experience in electrophysiology.

Job Information

Contract length:
1 or more years
Institution:
Weill Cornell Medical College
Department:
Biochemistry

Contact Information

Jeremy Dittman
1300 York Ave
Room E108
Weill Cornell Medical College
New York, NY 10065

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