Ph.D. Student in Magdeburg/Germany

Connecting European Neuroscience

Ph.D. Student in Magdeburg/Germany

13 June 2018

Ph.D. Student in Magdeburg/Germany

Job ID
19171
Place
Magdeburg/Germany

Description

The communication between synapse and nucleus is crucial for activity-depedent gene expression in the context of synaptic plasticity and stability. In our previous work we could show that proteins that directly interact with NMDAR subunits can be transported to the nucleus leading to sustained changes in gene expression (Proepper et al., EMBO J 2007; Dieterich et al., PLoS Biol. 2008; Kindler et al., J Biol Chem, 2009; Karpova et al., Cell 2013; Spilker et al., PLoS Genet. 2016; Dinarmaca et al. eLife 2016; 2016; Kravchick et al., EMBO J 2016; Grochowska et al., EMBO Rep 2017 / see Jordan & Kreutz, Trends in Neurosci. 2009 and Panayotis et al., Trends in Neurosci. 2015 for review). Several transgenic mouse models have been recently generated in our lab to study these processes in vitro and in vivo.

We are seeking for a highly motivated PhD student to address how gene expression induced by synapto-nuclear protein messenger feeds back to synaptic function in mechanistic terms. NPlast has its research focus on Molecular & Cellular Neuroscience and employs a broad spectrum of advanced techniques. For more information see www.kreutzlab.com. The suitable candidate should have a general background in Cell Biology. The project requires expertise in live-imaging (microfluidics, primary neurons and organotypic slices with SDCM, TIRF, 2P and STED microscopy) combined with electrophysiology. Previous experience in one of these techniques is a plus but no prerequisite. We offer a stimulating and challenging scientific environment in an international and dynamic team. Equal opportunities for women and men are ensured.

Applications should include a cover letter stating research interests and previous experience, a CV and contact information of two referees. Correspondence and inquiries should be directed to Dr. Camilla Fusi (cfusi@lin-magdeburg.de) and Dr. Anna Karpova (akarpova@lin-magdeburg.de). Applications should be send to Michael R. Kreutz (michael.kreutz@lin-magdeburg.d

Job Information

Employment start date:
2018-07-15
Contract length:
3+1
Institution:
Leibniz Institute for Neurobiology
Department:
Research Group Neuroplasticity

Contact Information

Dr. Michael R. Kreutz
Leibniz-Institut für Neurobiologie
FG Neuroplastizität
Brenneckestraße 6
39118 Magdeburg
Phone
0391626394181
Email
michael.kreutz@lin-magdeburg.de
Website
http://kreutzlab.com/

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