Connecting European Neuroscience

Post-doctoral position in MARSEILLE/France

11 July 2018

Post-doctoral position in MARSEILLE/France

Job ID
19584
Place
MARSEILLE/France

Description

The project aims at deciphering, anatomically and functionally, the circuitry of a poorly known neuronal population present around the central canal (CC) of the spinal cord and in contact with the cerebrospinal fluid (CSF-cNs).
The SpiCCI Team was one of the first to characterize CSF-cN properties in the mouse and established as leader in the field with a long-standing expertise in cellular neurophysiology and imaging. By using a set of transgenic mouse models (Cre-Lox technology from PKD2L1-Cre mice) enabling the selective manipulation of CSF-cNs, our team develops a multidisciplinary approach combining in vitro and ex-vivo electrophysiology with Ca2+ imaging, optogenetic as well as viral retrograde neuronal tracing.
The Project is part of a recently awarded international ANR grant in collaboration with Dr N ZAMPIERI (MDC, Berlin) and involves applying targeted viral neuronal tracing approaches combined to electrophysiological and imaging techniques in in vitro and ex-vivo spinal cord preparations. The principal objective will be to characterize CSF-cN circuitry in the spinal cord and demonstrate the interaction with the spinal motor network.
The successful Candidate will have a PhD in neuroscience, some postdoctoral experience with a proven expertise in cellular electrophysiology (slice patch-clamp) and imaging.
She/He should have experience in small animal surgery (Animals Training Course). A background in molecular biology (transgenic mouse model, viral neuronal tracing techniques) as well as knowledge in programming and analysis software (eg. Python, Matlab, R statistic) would be a plus. The project will be conducted under Dr Wanaverbecq supervision, but the candidate should be autonomous and capable of conducting the assigned line of research.
Send CV, a cover letter detailing research experience and interests, and contact details for at least two referee.

Job Information

Employment start date:
2018-09-01
Contract length:
2 year with renewal possible
Institution:
Aix Marseille University
Department:
Institut de Neurosciences de la Timone UMR7289

Contact Information

Nicolas Wanaverbecq
27 Boulevard Jean Moulin

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