Connecting European Neuroscience

Ph.D. Student in Innsbruck/Austria

06 November 2018

Ph.D. Student in Innsbruck/Austria

Job ID
20648
Place
Innsbruck/Austria

Description

A position on Neuroinflammation and pain in a mouse model for Fabry disease has become available. This studentship is part of the TOBeATPAIN project based at the Div. Physiology, based at the Medical University Innsbruck under supervision of Prof. M. Kress and Dr. M. Langeslag (https://www.i- med.ac.at/dpmp/physiologie) and co-supervised by Prof. R. Chaudhuri at King’s College London.
TOBeATPAIN is a MSCA Innovative Training Network, which offers a research-based training programme for 11 young scientists on how to investigate the underlying mechanisms of pathological pain in neurodegenerative diseases, musculoskeletal conditions and peripheral neuropathies, with the ultimate aim to delineate novel therapeutic strategies.
The project will explore the pathogenesis of pain in Fabry disease, an X-linked lysosomal storage disorder due to deficiency of the enzyme α-galactosidase A. The importance of innate immune system-mediated regulation of cytokine expression in the peripheral nerve, spinal cord and brain will be assessed. The candidate will perform immune stainings to explore immune cells in the nervous system of a mouse model of FD, profile cytokine mRNA and microRNA expression and perform associated target gene analysis (qPCR) and identify mechanistic pathways through a bioinformatics approach followed by validation in vivo.
Please submit your full application (including full c.v., copies of certificates, motivational letter and career goals) with two letters of reference to andrea.deutschmann@i-med.ac.at; phone: +43-512-9003-70800.
Requirements:
- At the time of the appointment applicants must not have resided or carried out her/his main activity (work, studies, etc.) in the country of the host institute for more than 12 months in the 3 years immediately before appointment under the project.
- Applicants shall also be in the first four years of her/his research career at the time of appointment by the host organisation and have not been awarded a doctoral degree.

Job Information

Closing date:
2018-11-15
Employment start date:
2019-02-01
Contract length:
3 years
Institution:
Medical University Innsbruck
Department:
Division of Physiology

Contact Information

Michaela Kress
Schöpfstrasse 41/EG
Phone
+46 512 9003 70800
Email
michaela.kress@i-med.ac.at
Website
http://physiologie.uibk.ac.at

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