Connecting European Neuroscience

Post-doctoral position in Bordeaux/France

18 February 2019

Post-doctoral position in Bordeaux/France

Job ID
21544
Place
Bordeaux/France

Description

A postdoctoral research position is available immediately, for up to 3 years, to study the structure and therapeutic targeting of disease-linked neuronal cell-surface protein complexes.

The project will focus on novel neuronal ligand-receptor interactions, and is an active collaboration with laboratories at the VIB & KU Leuven Center for Brain & Disease Research, Leuven, Belgium (https://cbd.vib.be/).

Recent relevant publications illustrating the methodologies include Elegheert J. et al., Neuron, 2017; Elegheert J. et al., Science, 2016, and Elegheert J. et al., Nature Protocols, 2018.

The work will involve mammalian protein production, protein chemistry, biophysical interaction analysis, X-ray crystallography, and discovery of nano- and antibodies.

The candidate must hold a PhD degree and have less than two years of post-doctoral experience at the start of the contract. The candidate should have a solid background in molecular biology, biochemistry and/or structural biology. Experience with (i) mammalian expression systems (HEK293 cell lines), (ii) biophysical analysis methods, and (iii) X-ray crystallography, is preferred but not mandatory. The candidate should be highly motivated, a team player, and have a can-do problem-solving attitude.

The project will be carried out under the supervision and mentorship of Dr. Jonathan Elegheert at the IINS in Bordeaux, France, which is recognised for its expertise in molecular and cellular neuroscience, and which is further embedded within the Bordeaux Neurocampus (http://www.bordeaux-neurocampus.fr/en/index.html), a vibrant community of more than 600 neuroscientists.

The IINS harbors state-of-the-art facilities for protein biochemistry, molecular biology, mammalian cell culture and animal models, as well as microscopic imaging in the on-site Bordeaux Imaging Center (BIC; http://www.bic.u-bordeaux.fr/).

Job Information

Contract length:
3 years (1 + 2)
Institution:
CNRS / University of Bordeaux
Department:
Interdisciplinary Institute for NeuroScience (IINS)

Contact Information

Jonathan Elegheert
Interdisciplinary Institute for NeuroScience (IINS)
UMR5297 CNRS / UB
University of Bordeaux
Centre Broca Nouvelle-Aquitaine
146 rue Léo Saignat
33076 Bordeaux Cedex
France

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