Connecting European Neuroscience

Post-doctoral position in London/UK

18 March 2019

Post-doctoral position in London/UK

Job ID
21779
Place
London/UK

Description

We seek to appoint two postdoctoral research associates (PDRA) and one PhD student to join an interdisciplinary team of engineers and neuroscientists researching how the mechanical properties of neurons and glia change in the ageing brain, particularly in the hippocampus, and the neurophysiological consequences of these mechanical perturbations.

Successful applicants will join an international network of bioengineers using innovative approaches to tackle major, unmet challenges in ageing, dementia and neurodegenerative diseases. The positions offer access to world-leading institutions for the study of mechanobiology, neurophysiology, healthcare engineering, and neurodegenerative disorders.

These positions will be carried out in the laboratories of Dr Emad Moeendarbary (University College London) and Dr Graham Sheridan (University of Brighton).

You will be required to:
• Perform molecular biological techniques, including PCR, Western blot and ELISA
• Perform neuronal, glial and organotypic brain slice cultures
• Perform in vivo behavioural studies
• Prepare acute hippocampal slices for atomic force microscopy, electrophysiology, live-cell calcium imaging, and immunofluorescence
• Work effectively as a team member and collaborate with local partners

You should have a range of interdisciplinary skills. In particular, we invite candidates with prior expertise in several of the following:
• Theoretical and applied engineering
• Bioengineering, mechanobiology, microfluidics or atomic force microscopy
• Electrophysiology (e.g. patch-clamp recordings) and/or live-cell calcium imaging applied to neurophysiological research
• Neuroinflammation, neurodegenerative diseases or the ageing brain
• Culturing primary rodent neurons, glial cells, or brain slices
• Advanced super-resolution or traction force microscopy techniques


Informal enquiries should be made to Emad Moeendarbary (e.moeendarbary@ucl.ac.uk) and Graham Sheridan (g.sheridan@brighton.ac.uk)

Job Information

Employment start date:
2019-09-01
Contract length:
30 months (2.5 years)
Institution:
University College London
Department:
Mechanical Engineering

Contact Information

Graham Sheridan
School of Pharmacy & Biomolecular Sciences
Phone
+441273642030
Email
g.sheridan@brighton.ac.uk

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