Connecting European Neuroscience

Post-doctoral position in Nottingham/UK

07 May 2019

Post-doctoral position in Nottingham/UK

Job ID


Applications are invited for a Postdoctoral Research Associate position in Dr Graham Sheridan’s group (in the University of Nottingham) to study how ageing and neurodegeneration may impact the mechanical properties of neurons, glial cells and brain tissue. The successful candidate will investigate the neurophysiological consequences of altered mechanotransduction in hippocampal neurons and glia. Using electrophysiology and live-cell calcium imaging techniques, they will study the role of mechanosensitive ion channels in neuronal and glial calcium signalling and in regulating synaptic plasticity.

The work will be carried out in the laboratory of Dr Graham Sheridan in the School of Life Sciences, University of Nottingham. Current lab webpage:

Applicants should have a range of interdisciplinary skills. In particular, candidates with a proven track record in several of the following techniques are encouraged to apply:
- Electrophysiology (e.g. patch-clamp recordings)
- Live-cell calcium imaging in neurons or acute brain slices
- In vivo models of neuroinflammation/ neurodegeneration
- Computer programming and automated image analysis
- Culturing primary rodent neurons, glial cells, or organotypic brain slices
- Induced pluripotent stem cell (iPSC) models of neurodegenerative disease
- Traction force microscopy
- Proteomics
- Immunofluorescence and confocal microscopy
- Molecular biology techniques, including qPCR, Western blot, ChIP assays, or ELISA.

Funding is available for 2 years in the first instance.

Deadline for applications: 19th May 2019

Proposed start date: 1st August 2019

For informal enquiries, email Graham Sheridan (

Official applications must be submitted via the UCL website, using the instructions outlined here:

Job Information

Closing date:
Employment start date:
Contract length:
2 years
University of Nottingham
Physiology, Pharmacology and Neuroscience

Contact Information

Graham Sheridan
Current address: University of Brighton

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