Connecting European Neuroscience

Post-doctoral position in PARIS/France

11 August 2019

Post-doctoral position in PARIS/France

Job ID
24234
Place
PARIS/France

Description

Two ERC-funded postdoctoral positions in Neurosciences
Charrier lab - Ecole Normale Supérieure, Paris.

The synapse is a nanoscale machine, which transfers, integrates and stores information in brain circuits. Its function relies on multimolecular networks of interactions whose composition and dynamics shape synaptic transmission. Small changes in the molecular organization of synapses can lead to profound modifications of behavioral and cognitive abilities, as frequently observed in neurodevelopmental and psychiatric disorders. Small changes also appeared during human evolution. Although poorly characterized, they underlie distinctive developmental and physiological properties of human neurons that are at the core of what makes us humans. The projects will investigate the regulation of synaptic development or plasticity by molecular pathways linked to human evolution. They will employ a multidisciplinary approach based on sparse in vivo manipulations in intact brain circuits, high-resolution microscopy, electrophysiology and proteomics in mouse and human models. The goal is to characterize fundamental mechanisms that are common to all mammals and uncover regulations that are specific to humans.

We are located at the Ecole Normale Supérieure in Paris, France (IBENS, Inserm 1024 - CNRS 8197). The institute provides an exceptional scientific environment and a vibrant international community for students and post-docs in the center of Paris.

We are seeking highly motivated, independent and creative individuals to join the team. The candidates should have a PhD in neurosciences, cellular/developmental biology or in a related field, and a strong interest in synapses. Background in molecular and cellular biology, electrophysiology, microscopy or stem cell biology will be appreciated.

To apply, please contact Cécile Charrier at cecile.charrier@ens.fr with your CV, a cover letter explaining your motivations and previous work, and three references for recommendation.

Job Information

Closing date:
2019-12-31
Contract length:
up to five years (ERC-funded)
Institution:
Ecole Normale Supérieure, Inserm
Department:
IBENS - CNRS UMR8197 - INSERM U.1024

Contact Information

Cécile Charrier
Biology Institute of the Ecole Normale Supérieure,
Inserm U1024 - CNRS 8197
46 rue d'Ulm, 75005 Paris, France

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