Connecting European Neuroscience

Post-doctoral position in Bristol/UK

10 September 2019

Post-doctoral position in Bristol/UK

Job ID
24382
Place
Bristol/UK

Description

We are looking for a self-motivated and talented junior scientist to study the role of altered microRNA activity on dendritic spine morphology and synaptic function in mouse models for Alzheimer’s disease. The project will build on our recent discovery that Argonaute 2 (Ago2) phosphorylation regulates the local translation of specific mRNAs and is required for structural and functional plasticity (Rajgor et al., EMBO Journal 2018).


The work will be based initially in the laboratory of Jon Brown at Exeter University for in vivo molecular interventions (adenovirus and antagomir injections) and ex vivo slice electrophysiology. This will be followed by biochemical and cell imaging techniques in Jonathan Hanley’s lab at the University of Bristol.


Applicants must have a PhD with relevant lab experience including in vivo rodent brain surgeries, and are expected to have at least one 1st author article published in a quality peer-reviewed journal. Please submit a cover letter, CV and the names of at least two referees to jon.hanley@bristol.ac.uk.

Job Information

Closing date:
2019-10-04
Employment start date:
2020-01-13
Contract length:
3 years
Institution:
University of Bristol
Department:
School of Biochemistry

Contact Information

Jonathan Hanley
School of Biochemistry,
Faculty of Life Sciences,
University of Bristol,
University Walk,
Bristol,
BS8 1TD
Phone
+44(0)117 331 1944
Email
jon.hanley@bristol.ac.uk

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