Connecting European Neuroscience

Post-doctoral position in Paris/France

06 November 2019

Post-doctoral position in Paris/France

Job ID
25854
Place
Paris/France

Description

We are looking for a postdoctoral fellow with expertise in electrophysiology, optogenetics, in vivo recordings and/or behavior and who has a special interest in regeneration. The post-doc candidate will integrate our team located in the new Institut of Psychiatry and Neuroscience of Paris (IPNP) inside Sainte-Anne Hospital, a highly stimulating environment.

When myelination is impaired or myelin is destroyed in the CNS, cognitive, motor and sensory functions are compromised. Despite the low regeneration capacity of the CNS, a spontaneous production of newly formed oligodendrocytes and a partial myelin repair can occur in response to a demyelinating injury. We recently showed that a moderate neuronal activity in vivo improves myelin repair by increasing both the density of OLs and myelin production in demyelinated lesions, inducing a remarkable functional recovery (Ortiz et al., 2019). The present project aims to determine the mechanisms allowing neuronal activity to improve myelin repair and, in turn, action potential conduction.

Recent relevant publications of the team:
• Orduz D et al., (2019) Nat Commun 10:4249
• Ortiz FC et al. (2019) JCI Insight 4(9):e123434
• Balia M et al. (2017) Glia 65(11):1821-1832
• Wake H et al. (2015) Nat Commun 6:7844.
• Orduz D et al. (2015) eLife 4:e06953

Job Information

Contract length:
2 years
Institution:
Institute of Psychiatry and Neuroscience of Paris
Department:
Inserm

Contact Information

Maria Cecilia Angulo
Team: Interactions between neurons and oligodendroglia in myelination and myelin repair Institute of Psychiatry and Neuroscience of Paris (IPNP)
INSERM U1266
102-108, rue de la Santé
75014 Paris
FRANCE

Jobs Archive

loading