Connecting European Neuroscience

Post-doctoral position in Milan/Italy

27 November 2019

Post-doctoral position in Milan/Italy

Job ID
26038
Place
Milan/Italy

Description

IRCCS Ospedale San Raffaele (OSR) is a University and Research Hospital which integrates basic and clinical research through a translational approach. The institute aims at understanding the mechanisms underlying a variety of human diseases and at identifying new targets and therapeutic strategies to treat them. Among the principal clinical area of investigation: central and peripheral nervous systems pathologies, tumors, immuno-mediated, infectious, genetic, cardiovascular and metabolic diseases (https://research.hsr.it/en/ospedale-san-raffaele/index.html).

At IRCCS Ospedale San Raffaele, a post-doctoral research-fellow position is immediately available in the laboratory of Prof. Alessandra Bolino to work in the field of myelin biology and inherited disorders of the peripheral nervous system (PNS).

One main interest of the laboratory is to understand how Schwann cells, glial cells of the PNS, coordinate radial and longitudinal growth to form myelinated fibers in the nerve. While several key molecules and signals inducing differentiation and myelination during development have been recently identified, much less is known about mechanisms that coordinate longitudinal growth to form mature myelin. In this project, we will further investigate molecular pathways recently identified in the laboratory that control myelin elongation along the axon and that are disrupted in a number of inherited disorders of the PNS. To this aim, a combination of in vivo and ex vivo models (primary myelin-forming cultures) will be used as well as several approaches including proteomic analyses, biochemistry, and cell biology.

ELIGIBILITY CRITERIA: We are looking for highly motivated scientists who wish to advance in their academic training and consolidate the research experience in cell biology and neuroscience.
Previous research experience in cell biology and/or molecular biology is required.

Job Information

Closing date:
2020-02-29
Employment start date:
2020-03-01
Contract length:
3 years
Institution:
IRCCS Ospedale San Raffaele
Department:
Division of Neuroscience

Contact Information

Alessandra Bolino
Human Inherited Neuropathies Unit
Division of Neuroscience
IRCCS Ospedale San Raffaele
Via Olgettina 60
20132 Milan-Italy

Jobs Archive

loading