Connecting European Neuroscience

Post-doctoral position in Genova/Italy

01 August 2020

Post-doctoral position in Genova/Italy

Job ID
27560
Place
Genova/Italy

Description

Senior Post-doctoral position in “Innovative strategies for the modulation of transcriptional activity in brain diseases”
The Center for Synaptic Neuroscience and Technology at the Italian Institute of Technology (IIT) in Genova is opening a Senior Researcher position under the supervision of prof. Fabio Benfenati.
The research project will investigate the role of transcriptional regulation of neural genes in the control of synaptic plasticity, neuron survival and network excitability. Particular attention will be devoted to the role of transcriptional regulation by the repressor REST/NRSF, the mechanisms of regulation of its neuronal expression and its impact in higher cognitive functions and pathogenesis of central nervous system diseases. This will include development of area-specific conditional REST knockout models, generation of promoter-specific AAV viral vectors to specifically knockout REST in neurons and specific brain areas and in vivo testing of optogenetic devices able to switch REST repressor activity on and off.

The successful applicant should have a PhD in Neuroscience, Molecular Biology, Biotechnology or similar, a previous postdoctoral experience, with an in-depth expertise in neuronal cell and molecular biology, gene editing and generation of targeted viral vectors. Experience in surgery, stereotaxic injections and optogenetics will be considered a plus.
The position is a 2-year contract that is renewable up to 5-years. Salary and benefits are competitive for international standards.
Please submit your application (deadline September 30, 2020), including CV, 3 representative papers and 2-page research statement to fabio.benfenati@iit.it quoting “Postdoc position in Innovative strategies for modulating transcriptional activity in brain diseases” in the subject line. Candidates must also request reference letters to be sent directly by the referees to fabio.benfenati@iit.it

Job Information

Closing date:
2020-09-30
Employment start date:
2021-01-01
Contract length:
2 year initial contract, renewable up to 5 years
Institution:
Italian Institute of Technology
Department:
Center for Synaptic Neurosscience and Technology

Contact Information

Fabio Benfenati
Largo Rosanna Benzi
16132 Genova Italy

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