Connecting European Neuroscience

Ph.D. Student in ORLEANS/France

18 October 2020

Ph.D. Student in ORLEANS/France

Job ID
27855
Place
ORLEANS/France

Description

In vitro evaluation of the pharmacological properties of neonicotinoids, sulfoximines and butenolides on insect and mammalian neuronal nicotinic acetylcholine receptors.
Neuronal nicotinic acetylcholine receptors (nAChRs) are of particular interest because they are the main target of neonicotinoid insecticides, which are important in agriculture and veterinary medicine for controlling insect pests, and preventing transmission of insect borne diseases.
In the present study, we aim to further characterize the pharmacological properties of mammalian neuronal nAChRs, in particular the binding properties of neonicotinoid, sulfoximine and butenolide insecticides. The project will involve to compare insect and mammalian neuronal nAChRs.
Two main strategies will be used : (1) electrophysiological recordings using Two-electrode voltage clamp and (2) calcium imaging method. The hired Ph.D student will have to perform cRNA preparation, oocyte injection, voltage clamp and calcium imaging recordings.
A pre-selection will be made based on documents provided by candidates (Complete CV, letter of recommendation, the results obtained in the master program,…).
The university of Orléans is located in the south of Paris (1h15 from Paris) and 20 min from the downtown of Orléans. It comprises 26 research laboratories and around 20 000 students. Life in Orléans is wonderful and not expensive. The Ph.D student could live in the downtown of Orléans like many students. He/Her will have access to all laboratory’s equipment.
Salary : between 1400-1450 €/month (health insurance is paid by the University)

Job Information

Closing date:
2021-01-01
Employment start date:
2021-01-05
Contract length:
3 years (36 months)
Institution:
Université d'Orléans
Department:
Equipe Entomologie et Biologie Intégrée

Contact Information

Steeve Thany
LBLGC USC INRAE 1328
Unveirsity of Orleans
bat Physique-Chimie, 1er etage
1 rue de Chartres
45067 Orleans, France
Phone
(33) 238 41 70 58
Email
steeve.thany@univ-orleans.fr

Jobs Archive

loading