Connecting European Neuroscience

Ph.D. Student in Aarhus/Denmark

19 October 2020

Ph.D. Student in Aarhus/Denmark

Job ID
27857
Place
Aarhus/Denmark

Description

PhD project on mRNA architecture of the NMDA receptor gene in synaptic plasticity

The Center for Proteins in Memory (PROMEMO) at Aarhus University invites applications for a PhD fellowship at the Department of Molecular Biology and Genetics. The project will be jointly supervised by Prof. Poul Nissen, associate professor Hanne Poulsen and assistant professor Magnus Kjærgaard. The starting date is February 2021 or soon thereafter.

Memory and learning require the strength of synaptic connections to be adjusted following synaptic stimulation. At the molecular level, this requires production of plasticity-related proteins and their subsequent delivery to synapses. Plasticity-related proteins are often translated locally in dendrites and thereby targeted to specific nearby synapses.

This project aims to understand how translation of the genes of the NMDA receptors is regulated spatially and biochemically. The project will use fluorescence and cryo-electron tomography, mouse viral injection, and in vitro RNA/protein biochemical assays.

Read more here: https://phd.nat.au.dk/for-applicants/apply-here/november-2020/mrna-architecture-of-the-nmda-receptor-gene-in-synaptic-plasticity/

Job Information

Closing date:
2020-10-31
Employment start date:
2021-02-01
Institution:
Aarhus University
Department:
Dept. Molecular Biology and Genetics

Contact Information

Karen Bech
Dept. Molecular Biology and Genetics
Gustav Wieds Vej 10C
8000 Aarhus C
Denmark

Applicants seeking further information are invited to contact:
Associate professor Hanne Poulsen (hp@mbg.au.dk)

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