Professional and academic career
1981 – 1987 Studies of Medicine, University of Bonn, Germany
1982 – 1985 Studies of Physics, University of Bonn, Germany
1982 – 1987 Studies of Philosophy, University of Bonn, Germany
1999 Habilitation (venia legendi) for Physiology, Humboldt University Berlin
1991 MD (Dr. med. ), University of Heidelberg, Germany.
2002 – present: Professor, Chair of Neurophysiology, University of Heidelberg
1998 – 2002 Senior research assistent, Humboldt University Berlin (Charité)
1997 – 1997 Senior Research fellow, University of Birmingham, UK
1994 – 1998 Research Assistant, Humboldt University Berlin (Charité)
1992 – 1994 Scientific Assistant, Department of Physiology, Cologne University
1990 – 1991 Internship (Elective: Neurology), Remscheid, Germany
1987 - 1990 MD student, MPI Göttingen and Heidelberg, Germany.
Honors and awards
2010 - Fellow of "Marsilius Kolleg" (Center for Advanced Studies, Heidelberg University)
1996 European Research Grant
1980–1990 Fellowship by the "Studienstiftung des Deutschen Volkes".
General and administrative experience
2001 - Expert Commission “Physiology” at the National Institute for Medical Exams
2006- Vice Director, Interdisciplinary Center for Neuroscience at Heidelberg University
2009 - 2013 Member of the Review Board for Neuroscience of the DFG (Deutsche Forschungsgemeinschaft), German Research Foundation
2012 - Speaker of the Review Board for Neuroscience of the DFG (Deutsche Forschungsgemeinschaft), German Research Foundation
2011- Board Member of the German Physiologic Society, 2012/2013 president
Contributing Editor: European Journal of Neuroscience, IBRO ́s Neuroscience.
Experience in financial matters
Since 2002: Board member and treasurer of the NWG (Neurowissenschaftliche Gesellschaft), German Society for Neuroscience;
2003-2005, 2011-2013: Administrative Director of the Institute for Physiology and Parthophysiology, University of Heidelberg.
My research focusses on the mechanisms underlying coordinated patterns of neuronal activcity in neuronal networks. Such patterns do often take the form of synchronous membran potential oscillations which entrain discharges of selected neurons. Important research questions are:
- How are active neurons recruited into activity patterns?
- How is the temporal precision of firing during entowrk oscillations achieved?
- How is unrelated background activity suppressed during defined patterns?
- What are the salient features of oscillating cell ensembles?
- How do different (oscillating) patterns interact within and between networks?
- As a related aspect of cellular neurophysiology, we study plasticity of GABAergic synapses.
We use mainly with electrophysiological methods in vivo and in vitro, with emphasis on fast network oscillations in the mouse hippocampus. We apply our concepts to research on epilepsy, Alzheimer-related molecules and sleep regulation.
- Yanovsky Y, Ciatipis M, Draguhn A, Tort AB, Brankačk J. (2014) Slow oscillations in the mouse hippocampus entrained by nasal respiration. J Neurosci. 34:5949-5964.
- Traub RD, Schmitz D, Maier N, Whittington MA, Draguhn A (2012) Axonal properties determine somatic firing in a model of in vitro CA1 hippocampal sharp wave/ripples and persistent gamma oscillations. Eur J Neurosci 36:2650-2660.
- Bahner F, Weiss EK, Birke G, Maier N, Schmitz D, Rudolph U, Frotscher M, Traub RD, Both M, Draguhn A (2011) Cellular correlate of assembly formation in oscillating hippocampal networks in vitro. Proc Natl Acad Sci U S A 108:E607-616.
- Reichinnek S, Kunsting T, Draguhn A, Both M (2010) Field potential signature of distinct multicellular activity patterns in the mouse hippocampus. JNeurosci 30:15441-15449.
- Hartmann K, Bruehl C, Golovko T, Draguhn A (2008) Fast homeostatic plasticity of inhibition via activity- dependent vesicular filling. PLoSOne 3:e2979.
- Buzsaki G, Draguhn A (2004) Neuronal oscillations in cortical networks. Science 304:1926-1929.
- Maier N, Nimmrich V, Draguhn A (2003) Cellular and network mechanisms underlying spontaneous sharp wave-ripple complexes in mouse hippocampal slices. JPhysiol 550:873-887.
- Draguhn A, Traub RD, Schmitz D, Jefferys JG (1998) Electrical coupling underlies high-frequency oscillations in the hippocampus in vitro. Nature 394:189-192.
Draguhn A, Verdorn TA, Ewert M, Seeburg PH, Sakmann B (1990) Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+. Neuron 5:781-788.