Connecting European Neuroscience

Krieglstein, Kerstin

Schools Committee Member (2012 - 2014)

Curriculum Vitae

1990-1992
Postdoc at the Dept. Mol. Biol. & Biochemistry, UC Irvine, (Group of Prof. A. Henschen)
1992-1999
Postdoctoral Researcher at the Institute of Anatomy & Cell Biology, Universities of Marburg and Heidelberg (Group of Prof. K. Unsicker)
1999-2001
Associate Professor of Anatomy (C3), University of Saarland, Homburg/Saar
2001-2007
Full Professor of Neuroanatomy (C4) and head of Department, University of Göttingen
2002-2007
Co-Founder, Area field coordinator, and steering committee member of DFG-centre of excellence "Molecular Physiology of the Brain"
2006
Visiting Scientist at the University of Helsinki, Inst. Biotechnology
October 2007-Present
Full Professor of Anatomy and head of Department of Molecular Embryology (W3), University of Freiburg
October 2009-Present
Chair of the Institute of Anatomy and Cell Biology, University of Freiburg
October 2010-Present
Vice dean for Strategic Developments and Research, Medical Faculty

Honours and Awards

1991
Award of the University of Marburg for an outstanding doctoral thesis
1995
Young scientist travel award ISN (Kyoto)
1996
Lectureship (ESN, Groningen)
1998-1999
Heisenberg-Fellowship of the DFG
1999
Wolfgang-Bargman-Prize of the Anatomical Society
2001
Saar-LB Prize
2008
Member of the Leopoldina
Since 2010
Fellow, Freiburg Institute for Advanced Studies, FRIAS, University of Freiburg

Administrative and organisational experience


Responsible Local Organizer of the Göttingen Meeting of the German
Neuroscience Society in 2005 and 2007
Member of the Feodor-Lynen Board of the AvH-Foundatio

Expertise in national or international training of students


2006-2012: Rapporteur of the DFG and Member of the DFG Senate for the Graduate Programme
2003-2011: Member of the Feodor-Lynen Board of the AvH-Foundation Member of the Speman Graduate School of Biology and Medicine

Research interests

Growth factors in nervous system development: induction and specification of neuronal phenotypes, regulation of neuron survival, ontogentic cell death, synaptogenesis, functions, signaling and contextual actions of TGF-betas and related proteins

    Selected Publications

  • Krieglstein K, Zheng F, Unsicker K, Krieglstein K (2011) More than being protective: Functional roles for TGF-ß signaling pathways at central synapses. TINS (in press). Review
  • Kunwar AJ, Rickmann M, Backofen B, Browski SM, Rosenbusch J, Schöning S, Fleischmann T, Krieglstein K, Fischer von Mollard G. Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. ProcNatl Acad Sci U S A. 2011 Feb 8; 108(6):2575-80
  • Vogel T, Ahrens S, Büttner N, Krieglstein K. Transforming growth factor beta promotes neuronal cell fate of mouse cortical and hippocampal progenitors in vitro and in vivo: identification of Nedd9 as an essential signaling component. Cereb Cortex. 2010 Mar; 20(3):661-71
  • Heupel K, Sargsyan V, Plomp JJ, Rickmann M, Varoqueaux F, Zhang W, Krieglstein K. (2008) Loss of transforming growth factor-beta 2 leads to impairment of central synapse function. Neural Develop. 3, 25
  • Roussa, Oehlke O, Rahhal B, Heermann S, Heidrich S, Wiehle M, Krieglstein K (2008) TGF-b co-operates with Persephin for dopaminergic phenotype induction. Stem Cells 2, 1683-1694
  • Roussa, E., Wiehle, M., Dünker, N., Becker-Katins, S., Oehlke, O., Krieglstein, K. (2006) Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. Stem Cells 24, 2120-2129
  • v Bohlen und Halbach O, Schober A, Krieglstein K (2004) Genes, proteins, and neurotoxins involved in Parkinson’s disease. Prog. Neurobiol 73, 151-177. Review
  • Farkas L., Dünker N., Roussa E., Unsicker K., Krieglstein K. (2003) TGF-bs are essential for the development of midbrain dopaminergic neurons in vitro and in vivo. J Neurosci 23, 5178-5186
  • Dünker N, Schuster N, Krieglstein K. (2002) TGF-beta modulates programmed cell death in the retina of the developing chick embryo. Development. 128, 1933-42
  • Krieglstein K, Richter S, Farkas L, Schuster N, Dünker N, Oppenheim RW, Unsicker K. (2000) Reduction of endogenous transforming growth factors beta prevents ontogenetic neuron death. Nat Neurosci 3, 1085-90

Kerstin Krieglstein

Kerstin KrieglsteinChair of the Institute of Anatomy & Cell Biology
University of Freiburg
Albertstr 17
D-79104 Freiburg
Germany

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