Connecting European Neuroscience

Matsas, Rebecca

Schools Committee Member (2010 - 2014)

Curriculum Vitae

Education


1976: BSc in Chemistry, University of Athens, Greece
1980: PhD in Biochemistry, University of Essex, UK
1981-1985: Post-doctoral Research Fellow in Neurobiology, University of Leeds, UK (with A. J. Turner)

Positions and employment


1985-1989:
Researcher, Hellenic Pasteur Institute
1989-1998:
Senior Investigator; Head of Laboratory of Cellular and Molecular Neurobiology, Hellenic Pasteur Institute
1992:
Visiting scientist, Ophthalmology Department, University of Tubingen Medical School, Germany
1998 - date:
Research Director; Head, Laboratory of Cellular and Molecular Neurobiology, Hellenic Pasteur Institute
2002-2005:
General Director, Hellenic Pasteur Institute
2010 Jul-Sep:
Visiting Scholar, Harvard University Stem Cell Institute

Honours and Awards


Fulbright Foundation Research Scholar
Chevalier de l'Ordre National du Mérite, French Republic.
Member of the Editorial Board of GLIA
EMBO Research Fellow
Medical Research Council UK Research Fellow
Greek State Scholarship Foundation Studentship

Administrative and organisational experience/peer reviewer


National Representative in the European Neuroglial Network since its foundation in 1994 Director of the Hellenic Pasteur Institute 2002-2005 Past Member of the Executive Bureau of the International Pasteur Network and Regional Representative of the European Pasteur Institutes Past Member of the Council of Directors of the Hellenic Research Centress and Independent Research Institutes National Delegate in the Programme Committee of the European Commission 6th Framework Program: Life Sciences & Biotechnology for Health Founding member of the Hellenic Neuroscience Society, past Treasurer of the Society and currently Council member Chair of the Organizing and Scientific Committees of the 3rd European Meeting on Glial Cell Function in Health and Disease, 1998 Member of the Organizing/Scientific Committees of the 4th, 5th and 9th European Meetings on Glial Cell Function in Health and Disease; the 23rd Annual Hellenic Neuroscience Society Meeting, 2009 and other past Meetings of the Society; the 60th Meeting of the Hellenic Society for Molecular Biology and Biochemistry, 2009; the joint International Society of Neurochemistry/European Society for Neurochemistry Meeting, 2010 Schools Organizer: FENS/IBRO Winter School: NEURAL STEM CELLS from specification and nervous system patterning to therapies for neurodegenerative diseases, Kitzbuhel, Austria, 2003; FEBS/EMBO Advanced Course: From differentiation to death of nerve cells, Spetses, Greece, 2001 Expert evaluator in reviewing panels of the European Commission for the 5th and 7th Framework Program; peer-reviewer for the National Swiss Foundation, the Spanish Ministry of Science and Innovation, the Cyprus Foundation, the Hellenic General Secretariat for Research & Technology and other funding bodies and organizations.

Selected Publications

  • Makri G, Lavdas AA, Katsimpardi L, Charneau P, Thomaidou D and Matsas R (2010) Transplantation of embryonic neural stem/ precursor cells overexpressing BM88/Cend1 enhances the generation of neuronal cells in the injured mouse cortex. Stem Cells 28:127-39.
  • Lavdas AA, Chen J, Papastefanaki F, Chen S, Schachner M, Matsas R and Thomaidou D(2010) Schwann cells engineered to express the cell adhesion molecule L1 accelerate myelination and motor recovery after spinal cord injury. Exp Neurol 221:206-16.
  • Sergaki MC, Guillemot F and Matsas R (2010) Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1. Mol Cell Neurosci, 44:15-29.
  • Katsimpardi L, M Gaitanou, CE Malnou, PM Lledo, P. Charneau, R Matsas and D Thomaidou (2008) BM88/Cend1 expression levels are critical for proliferation and differentiation of subventricular zone-derived neural precursor cells. Stem Cells 26:1796-807.
  • Politis PK, Makri G, Thomaidou D, Geissen M, Rohrer H, Matsas R. (2007) BM88/CEND1 coordinates cell cycle exit and differentiation of neuronal precursors. Proc Natl Acad Sci USA. 2104 (45):17861-6.
  • Papastefanaki F, Chen J, Lavdas AA, Thomaidou D, Schachner M, Matsas R. (2007) Grafts of Schwann cells engineered to express PSA-NCAM promote functional recovery after spinal cord injury. Brain 130:2159-74.
  • Lavdas AA, Franceschini I, Dubois-Dalcq M, Matsas R. (2006) Schwann cells genetically engineered to express PSA show enhanced migratory potential without impairment of their myelinating ability in vitro. GLIA 53(8):868-78.
  • Georgopoulou N, Hurel C, Politis PK, Gaitanou M, Matsas R, Thomaidou D. (2006) BM88 is a dual function molecule inducing cell cycle exit and neuronal differentiation of neuroblastoma cells via cyclin D1 down-regulation and retinoblastoma protein hypophosphorylation. J Biol Chem. 281:33606-20.
  • Papadodima O, Sergaki M, Hurel C, Mamalaki A, Matsas R. (2005) Characterization of the BM88 promoter and identification of an 88 bp fragment sufficient to drive neurone-specific expression. J Neurochem. 95:146-59.
  • Meintanis S, Thomaidou D, Jessen KR, Mirsky R, Matsas R. (2004) Novel method for studying myelination in vivo reveals that EDTA is a potent inhibitor of myelin protein and mRNA expression during development of the rat sciatic nerve. GLIA 48:132-44.

Dr. Rebecca Matsas

Dr. Rebecca Matsas
Hellenic Pasteur Institute
Department of Biochemistry
127, Vassilissis Sofias Ave
G-115 21 Athens
Greece

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