Connecting European Neuroscience

Angela Roberts

Programme Committee Member FENS Forum 2018

Curriculum Vitae

2009- Professor of Behavioural Neuroscience

2009 - Professorial Fellow, Girton College

2005- 2009 Reader in Behavioural Neuroscience

1999- 2009 Bye-fellow, Girton College

1996- 2009 University Lecturer, Dept. of Anatomy, University of Cambridge

1992- 1996 Royal Society University Research Fellow, Dept. of Experimental Psychology, University of Cambridge.

1992-1999 College Lecturer and Fellow, Girton College, University of Cambridge

1989-1992 Research Fellowship, Girton College, University of Cambridge.

1985-1992 Post-Doctoral Research Associate, Dept. of Experimental Psychology, University of Cambridge. Member of Editorial Boards:

2012- Associate Editor, Frontiers in Behavioral Neuroscience.

2011- Field Editor, International Journal of Neuropsychopharmacology.

Membership of Research and Grant committees:

2015- International Member, Brain Canada Scientific Advisory Forum

2013. Grant assessor, European Space agency 2013- Executive Committee member, Cambridge Neuroscience.

2009-2015 Executive committee member, Behavioural and Clinical Neuroscience Institute

2004-2008 MRC Neurosciences and Mental Health Board, College of Experts.

Honours and awards

2016 Fellowship of the Academy of Medical Science

1999 Merit award from the University of Cambridge

1996 Best paper of the Year in 1996 in Behavioral Neuroscience. Awarded by the American Psychological Association, Division 6.

1994 Merit award from the Royal Society.

General administrative and organisational experience

Organisation of public awareness events:

2017 Chair, two day public event, BRAINFEST, University of Cambridge

Organization of Research Symposia and meetings:

2016 Annual British Association of Psychopharmacology

2015 Festival of Neuroscience. British Neuroscience Association. Chair and Symposium speaker.

2015 Joint European Brain and Behaviour Society and European Behavioural Pharmacology Society meeting, Symposium.

2015 Annual Cambridge Neuroscience one day Seminar 2015 Bi-annual Cambridge Neuroscience Symposium

Membership of Committees of Learned Societies:

2015- Council member, British Association for Psychopharmacology.

2012- Council member, Understanding Animals in Research.

2010-13 Committee Member, ‘Animals in Research’ committee, Society for Neuroscience.

2000-02 Committee member, European Brain and Behaviour Society. 

Research interests

I am interested in the brain networks underlying cognitive and emotional behavior in primates. In particular, my research focuses on the executive control functions of the prefrontal cortex and related brain structures, including the basal ganglia and the amygdala, and the modulation of these circuits by the monoamines. The experimental approach combines neural, pharmacological, cardiovascular, neuroimaging and genetic techniques with sophisticated cognitive and emotional testing procedures. Since many of the behavioural tests that we use can also be administered to patients, our results directly extrapolate to the clinical setting. My research is currently funded by the Medical Research Council and the Wellcome Trust. 

Selected publications

10. Santangelo, A. M. Ito, M., Shiba, Y., Clarke H. F., Schut E. H. S. Cockroft G., Ferguson-Smith A. C., Roberts A. C. Novel primate model of serotonin transporter genetic polymorphisms associated with gene expression, anxiety and sensitivity to antidepressants. (2016) Neuropsychopharmacology 41:2366-76.

9. Jackson, S. A. W., Pears, A., Horst, N. K., Robbins, T. W., Roberts, A. C. Role of the Perigenual Anterior Cingulate and Orbitofrontal Cortex in Contingency Learning in the Marmoset. (2016) Cerebral Cortex 26:3273-84.

8. Clarke H. F., Horst N., Roberts A. C. Regional inactivations of primate ventral prefrontal cortex reveal two distinct mechanisms underlying negative bias in decision making. (2015) Proceedings of the National Academy of Sciences 112:4176-81.

7. Mikheenko Y., Shiba Y., Sawiak S., Braesicke K., Cockcroft G., Clarke H., Roberts A. C. Serotonergic, brain volume and attentional correlates of trait anxiety in primates. (2015) Neuropsychopharmacology 40:1395-404.

6. Walker S. C., Robbins T. W., Roberts A. C. Differential contributions of dopamine and serotonin to orbitofrontal cortex function in the marmoset. (2009) Cerebral Cortex 19:889-898.

5. Reekie Y. L., Braesicke K., Man M., Roberts A. C. (2008) Uncoupling of behavioral and autonomic responses following lesions of the primate orbitofrontal cortex. Proceedings of the National Academy of Sciences. 105:9787-92.

4. Agustín-Pavón C., Braesicke K., Shiba Y., Santangelo A. M., Mikheenko Y., Cockroft G., Asma F., Clarke H., Man M., Roberts A. C. Lesions of ventrolateral prefrontal or anterior orbitofrontal cortex in primates heighten negative emotion. (2012) Biological Psychiatry 72:266-272.

3. Clarke H. F., Walker S. C., Dalley J. W., Robbins T. W. and Roberts A. C. Cognitive inflexibility after prefrontal serotonin depletion is behaviourally and neurochemically specific (2007) Cerebral Cortex 17:18-27.

2. Clarke, H. F., Dalley, J. W., Crofts, H. S., Robbins, T. W., Roberts, A. C. Cognitive inflexibility after prefrontal serotonin depletion. (2004) Science 7:878-880.

1. Dias, R. Robbins, T. W., Roberts, A. C. (1996) Dissociation in the prefrontal cortex of affective and attentional shifting. Nature 380:69-72. 

Angela Roberts

Professor of Behavioural Neuroscience
Department of Physiology, Development and Neuroscience
University of Cambridge