Neurodevelopmental disorders are a group of different conditions in which the development of the central nervous system is disturbed. This includes developmental brain dysfunction, which can manifest as neuropsychiatric problems (Autism Spectrum Disorders, schizophrenia, fragile-X syndrome, down syndrome), or impaired motor function, learning, language or non-verbal communication. The generation of the appropriate diversity of neural cell types, their migration to correct sites in the brain and the establishment of precise connectivity with target cells are key developmental processes that may go awry, leading to brain dysfunction and neurological diseases.
During this advanced 3-week course, we will provide participants with a comprehensive theoretical and experimental/practical training on the most advanced methodologies and models in developmental neurobiology, in health and disease. World experts (both seniors and juniors) in the field of neural stem cells, brain patterning, neuronal migration, axon guidance or the genetics of human neurodevelopmental disorders will give stimulating lectures and design mini-projects to be carried out by the students.
This will give students a unique opportunity to become familiar with cutting-edge in vivo gene manipulation methods (electroporation, Crispr/Cas9, genetics...), 3D imaging technologies (SPIM and light sheet microscopy, tissue clearing, two-photon imaging...), time-lapse microscopy and cell tracking, advanced pluripotent stem cell culture (iPSCs, cortical progenitors and neurons derived thereof, organoids, organotypics…).
Herwig Baier (Max Plank Institute Neurobiology, Germany)
Paola Bovolenta (Centro de Biología Molecular Severo Ochoa (CBMSO) - CSIC, Spain)
Fiona Doetsch (University of Basel, Switzerland)
Elizabeth Engle (Harvard Medical School, USA)
Yukiko Gotoh (University of Tokyo, Japan)
John Rubenstein (UCSF School of Medicine, USA)
Fanny Mann (Developmental Biology Institute of Marseille (IBDM), France)
Oscar Marin (King’s college London, UK)
Laurent Nguyen (GIGA, University of Liège, Belgium)
Dietmar Schmucker (VIB-KU Leuven Center for Brain & Disease Research, Belgium)
Esther Stoeckli (University of Zurich, Switzerland)
Pierre Vanderhaeghen (University of Brussels ULB, Belgium)
the list of instructors
the course layout and the mini-projects
This course is organised in partnership with ERA-NET NEURON.
Applications were closed on 15 January 2018.
Fee : 3.500 € (includes tuition fee, accommodation and meals)
The CAJAL programme offers 4 stipends per course (waived registration fee, not including travel expenses). Please apply through the course online application form. In order to identify candidates in real need of a stipend, any grant applicant is encouraged to first request funds from their lab, institution or government.
Kindly note that if you benefited from a Cajal stipend in the past, you are no longer eligible to receive this kind of funding. However other types of funding (such as partial travel grants from sponsors) might be made available after the participants selection process, depending on the course.
ERA-NET NEURON offers grants to attendees who are part of an ERA-NET Neuron research group.
This course is sponsored by The Company of Biologists
Bordeaux Neurocampus, France
For enquiries, please contact: email@example.com