Bio-Neuroinformatics for the Neuroscientist course directors
Nicolas Le Novère is a neuroscientist and a computational biologist. Interests revolve around signal transduction, ranging from the molecular structure of membrane proteins involved in signal transduction to modelling signalling pathways. He also develops standards and services, including ontologies, databases and simulation software for computational systems biology.
He organised and taught in a variety of courses on systems biology and modelling in biology.
Neurobiologist interested in gene expression changes in various conditions including aneuploidies (trisomy 21), neurodegenerative diseases (Alzheimer’s disease) and pharmacological treatments. In her team she has also developed single cell gene expression analysis systems applied to single neurons. She has been using bioinformatics tools for data analysis and interpretation.
She teaches gene expression methods and analysis to Master student
Computational biologist working mainly in genomics. Currently, particularly interested in applications of high-throughput sequencing data. Her group develops methods for Next Generation Sequencing data analysis and de novo sequence assembly and its downstream analysis (genome assembly, variant detection, diversity analysis, biomarker identification, functional analysis). Methodological solutions are often a mix of algorithmics and machine learning.