Job ID: 109463

Postdoctoral Researcher – Neuroscience

Position: Post-doctoral Position

Deadline: 19 September 2023

Employment Start Date: 1 May 2023

Contract Length: 2 (possibility of extension)

City: Mainz

Country: Germany

Institution: University Medical Center, Johannes Gutenberg University Mainz

Department: Institute of Pathophysiology


The research group “Physiology and Pathophysiology of Synaptic Communication”, headed by Prof. Dr. Jakob von Engelhardt, of the Institute of Pathophysiology is seeking for a postdoctoral researcher. Our group investigates the physiology and the molecular basis of neuronal communication. A major research focus is the analysis of the role of glutamate receptors and of proteins that interact with the receptors in synaptic transmission and network activity (von Engelhardt et al., Science 2010, Khodosevich et al., Neuron 2014, Farrow et al., eLife 2015, Chen et al., Nature Communication 2018). Our research focuses on the role of glutamate receptor mediated transmission in neuronal function (e.g. synaptic plasticity, see von Engelhardt et al., Neuron 2008). To this end, we analyze different transgenic and knockout mouse lines as well as cell-cultures using various state-of-the-art techniques including in vitro and in vivo electrophysiology, molecular biology, protein biochemistry and microscopy.

See also:

The lab offers an excellent infrastructure in a unique research environment in Mainz. This includes opportunities for collaborations with research groups of the Focus Program Translational Neurosciences (FTN) of the Johannes Gutenberg University Mainz and the Rhine-Main Neuroscience Networks“ (rmn2).

Your responsibilities:

  • Investigation of synapse physiology and ionotropic receptor function with
  • electrophysiology with acute brain slices or cultured cells and/or
  • in vitro or in vivo imaging of neuron activity and/or
  • in vivo recording of neuron activity
  • handling of mice
  • virus injection into the brain of mice

The candidate should have:

  • a PhD in neuroscience, biology, or physics
  • training in electrophysiology or in vivo imaging or molecular biology
  • a course on laboratory animal science (FELASA, Category B) or the willingness to complete it
  • interest in synapse physiology and ionotropic receptor function
  • interest in learning new methods
  • enthusiasm and great commitment to independent and goal-oriented research
  • very good written and spoken proficiency in English and/or German
  • excellent communication and team-working skills
  • high motivation

For further information, please contact Prof. Dr. Jakob von Engelhardt (

The position will last for a two-year period with the possibility of extension. Employment, payment and social benefits are determined by the Public Sector Collective Agreement (TVL EG 13 / 100%). The job location is Mainz, Germany.

The Johannes Gutenberg University Mainz seeks to increase the number of female personnel in those areas where they are underrepresented and therefore explicitly encourages women to apply. The Johannes Gutenberg University Mainz is committed to employing disabled individuals and especially encourages them to apply.

Interested candidates should send their applications including a CV, a letter stating research interests and the names and contact information of two references to: