Job ID: 109802

Circuit Mechanisms of Neurodegeneration

Position: Post-doctoral Position

Deadline: 1 March 2024

Employment Start Date: 3 July 2023

Contract Length: 2 years

City: Munich

Country: Germany

Institution: University hospital Munich

Department: Institute of Clinical Neuroimmunology

Description:

We are seeking a highly motivated and passionate post-doctoral scientist to complement our group at the Institute of Clinical Neuroimmunology (www.klinikum.uni-muenchen.de/Institut-fuer-Klinische-Neuroimmunologie/en/forschung/ag_liebscher), University Hospital Munich, Ludwig-Maximilians-University (LMU) in Munich, Germany.

Using cutting edge two-photon imaging in awake, behaving mice combined with (chemo)genetic or pharmacological manipulations and behavioural and immunohistological assessments, we strive to elucidate cellular and circuit mechanisms driving neurodegenerative/neuroinflammatory processes in diseases such Amyotrophic Lateral Sclerosis or Autoimmune Encephalitis. To understand how molecular changes are linked to structural and functional alterations of single neurons and how these in turn affect neural circuits, we will chronically record from and genetically manipulate large populations of neurons and glia cells in behaving animals.

We offer excellent working conditions in a newly opened research center (BioMedical Center (BMC)) and a dynamic and highly collaborative multidisciplinary environment within not only our lab and the institute, but moreover our affiliated clinical unit, the many renowned research groups within the BMC and the Munich Excellence Cluster for Systems Neurology – SyNergy (www.synergy-munich.de). A competitive salary will be paid according to the German TV-L guidelines. Starting date is flexible but will preferentially be by July 2023, latest April 2024. Funding is secured for 2 years with possible extension.

Ideal candidates have prior experience in in vivo optical imaging or electrophysiology and good programming skills e.g. in Matlab/Python. Postdoctoral candidates should be able to work independently and to train PhD students. Applicants should hold a doctorate preferentially in neuroscience, physics, engineering or related fields. Proficiency in English and a team-oriented working attitude are indispensable.

Please send your application to sabine.liebscher@med.uni-muenchen.de.  The application should comprise a cover letter (previous own work, motivation for pursuing a post-doc), CV, list of publications and contact details of 2-3 references.