Job ID: 119593

Research technician position

Position: Technician

Deadline: 28 July 2024

Employment Start Date: 16 September 2024

Contract Length: One year in the first instance with the posibility of extension for three years.

City: London

Country: UK

Institution: University College London (UCL)

Department: Cell and Developmental Biology

Description:

Applicants are invited to apply for a research technician position to work in a project aimed at elucidating the function of Wnt signalling in synaptic connectivity. This is an exciting opportunity to join Professor Patricia Salinas lab at the main campus of UCL located at the heart of London.

The project is focused on elucidating the molecular mechanisms that regulate the formation and maintenance of synapses in the rodent brain and how deficiency in Wnt signalling contributes to synapse degeneration in Alzheimer’s disease. The work is based on previous published results (see Nuria Martin-Flores et al., eLife. 2024 Jan 29;12:RP89453 and Jones et al, Science Advances 2023 9 (2) DOI: 10.1126/sciadv.abo7421.

The applicant will use a range of state-of-the-art imaging techniques, transcriptomic and proteomic approaches as well as biochemical approaches and gene editing to understand the mechanisms that control the stability of synapses in the healthy brain and how synapses become vulnerable in neurodegenerative diseases.

Candidates should have a good first degree in a relevant life sciences discipline and have research skills applicable to this area of research.

The technician post will have a salary on Grade 6, in the range of £34,605–£39,980 (depending on qualifications and experience). The full-time position is for three years with a one year in the first instance.

Informal enquiries should be addressed to Professor Patricia Salinas (email: p.salinas@ucl.ac.uk). For an outline of the lab’s research interests see: https://salinaslabucl.co.uk/