Job ID: 119599

PhD-position in gene therapy and optogenetic signalling near Leipzig (Germany)

Position: Ph.D. Student

Deadline: 16 August 2024

Employment Start Date: 1 October 2024

Contract Length: 3 years

City: Halle (Saale)

Country: Germany

Institution: Martin-Luther-University Halle-Wittenberg

Department: Anatomy and Cell Biology

Description:

Externe Stellenausschreibung Reg.-Nr. 7-098/24-H

Creating Knowledge. Since 1502: Martin Luther University Halle-Wittenberg (MLU) offers a wide range of academic subjects in the areas of humanities, social sciences, natural sciences and medicine. The oldest and largest university in Saxony-Anhalt was created in 1817 when the University of Wittenberg (founded in 1502) merged with Friedrichs University Halle (founded in 1694). Today the university has 340 professors and 20,000 students. Research at the university focuses on nano and life sciences, the Enlightenment, society and culture.

The Department of Anatomy and Cell Biology, Medical Faculty of the Martin Luther University Halle-Wittenberg offers the temporary position (limited to 3 years) of a

 

Scientific Assistant (doctoral student) (m-f-x)

The position is immediately open and available as a part time employment (65 %).

Salary will be in accordance with the assigned tasks and personal qualification up to payment category 13 TV-L.

 

Tasks:

  • planning and execution of scientific projects regarding the role of B-Raf in the neurodegenerative disease Spinal Muscular Atrophy (SMA)
  • see Hensel et al., 2021, PNAS, https://doi.org/10.1073/pnas.2007785118
  • analysis of primary neuronal cells as an in vitro model of SMA
  • design and production of Adeno-associated viruses (AAV) for the transduction of neuronal cells
  • biochemical analyses of protein-protein interactions
  • establishment of an optogenetic sensor for the analysis of cellular signaling pathways
  • writing scientific papers and giving scientific talks
  • possibility for own qualification as doctorate candidate

 Requirements:

  • Master of Science or Diploma (in biochemistry, neurosciences, biology or similar)
  • previous experiences in cell culture techniques and protein biochemistry
  • sound basic knowledge in molecular biology, molecular cloning and imaging
  • keen interest in scientific work combined with critical thinking, initiative, and enthusiasm for lab work
  • high capacity for teamwork, resilience, flexibility, reliability, and a sense of responsibility
  • strong communication skills in English both oral and written
  • excellent software knowledge (Office, Excel, ImageJ, Prism)

Information about the lab:

The position is offered in the group of Prof. Hensel. The Hensel lab is a young  group. We offer an open and appreciative work environment in a highly motivated team. Our scientific program focuses on all aspects of the neurodegenerative disease Spinal Muscular Atrophy (SMA) and beyond. From cell lines to mouse models, from Western blots to Omics, from AAV-gene replacement therapies to confocal laser scanning microscopy – we employ a plethora of different approaches and methods doing basic research on clinically relevant topics in neurosciences.

In case of equal qualification, applications by severely disabled persons will be treated with priority. Women are explicitly encouraged to apply. Applicants with a non-German degree need to submit the Statement of Comparability for Foreign Higher Education Qualifications of the Zentralstelle für ausländisches Bildungswesen (https://www.kmk.org/zab/central-office-for-foreign-education).

For further questions, please contact anatomie@medizin.uni-halle.de, phone: 0345-557-1701, Fax: 0345-557-1701.

Please submit your application together with the usual documents under the Reg.-Nr. 7-098/24-H until 16.08.2024 to the Martin-Luther-Universität Halle-Wittenberg, Medizinische Fakultät, Institut für Anatomie und Zellbiologie, Große Steinstraße 52, 06097 Halle (Saale) or via email: anatomie@medizin.uni-halle.de

The job offer is under reservation by possible budgetary constraints.

The Martin Luther University Halle-Wittenberg does not cover any expenses related to job-applications. Documents will only be sent back if a stamped envelope is attached.

Applications via email are welcomed.