Job ID: 53972

Research Technician Gene therapy for epilepsy

Position: Technician

Deadline: 20 July 2021

Employment Start Date: 1 September 2021

Contract Length: 36 months in the first instance

City: London

Country: United Kingdom

Institution: University College London

Department: UCL Queen Square Institute of Neurology

Description:

Applications are invited for a Research Technician in the Department of Clinical and Experimental Epilepsy, UCL Queen Square Institute of Neurology. The mission of the Department is to transform the lives of people living with epilepsy for the better by identifying, understanding and correcting or preventing the underlying mechanisms leading to the epilepsies and associated comorbidities.
 
The post holder will support a programme to optimize and validate novel gene therapy tools that can be translated to treat drug-resistant epilepsy. The project will be supervised by DM Kullmann, MC Walker, S Schorge (UCL Department of Neuroscience, Physiology and Pharmacology) and G Lignani.
 
Applicants should have a BSc or equivalent in Biochemistry, Pharmacology, Medicinal Chemistry, Neuroscience or a related discipline. Experience of molecular biology methods (cloning, site-directed mutagenesis) and viral preparation is essential. 
 
IT proficiency at advanced user level (Spreadsheets, Word Processing, Database, Email, Web based applications, plus electrophysiological and imaging data processing, statistical analysis programs), good inter-personal skills with an ability to work co-operatively in a multidisciplinary setting and strong problem-solving abilities are also required. 
 
Experience of transgenic rodent colony maintenance, immunofluorescence and confocal microscopy is desirable, as is a Personal Licence from the UK Home Office to work with rodents.
A Job Description and Person Specification can be accessed at https://bit.ly/3gh1vXU