Job ID: 59798

DREADDs (Designer Receptors Exclusively Activated by Designer Drugs) for basic neuroscience and clinical translation

Position: Post-doctoral Position

Deadline: 1 October 2021

Contract Length: 30 months

City: London

Country: United Kingdom

Institution: University College London

Department: UCL Queen Square Institute of Neurology


We are looking for a Postdoctoral Research Fellow to design, optimize and validate chemogenetic tools to manipulate the excitability of neurons and brain circuits. The project will advance fundamental neuroscience and the treatment of neurological and psychiatric disorders. 
The post is available immediately and is funded by a grant from the Medical Research Council for 30 months in the first instance. Salary £36,028 – £41,228 per annum
Applicants should have (or be close to obtaining) a PhD or equivalent in molecular or cellular neuroscience or a related discipline. Experience of molecular pharmacology, medicinal chemistry, molecular modelling, and/or cellular electrophysiology is essential, as is a deep understanding of G-protein coupled receptor signalling. Expertise in cell-based arrays, immunofluorescence, confocal microscopy and working with viral vectors are desirable.   
Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at research assistant Grade 6B (salary £31,542 – £33,257 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.  If the PhD has not yet been granted, the final accepted version of the thesis must have been submitted to the degree-granting university by the start date in post.
Further details are available at;