Job ID: 60576

Technician in Neurobiologly

Position: Technician

Deadline: 15 December 2021

Employment Start Date: 1 February 2022

Contract Length: 3 years

City: Marseille

Country: France

Institution: Aix-Marseille University

Department: Institut de Neurosciences de la Timone

Description:

We are looking for a Neurobiology Engineer (Technician) to join the ‘Spinal Cord and CSF interface’ (SpiCCI) team at the Institut de  Neurosciences de la Timone a major laboratory located in Marseille whose objective is to develop high-level research in neuroscience and neurophysiologie, from cellular to cognitive levels, and to break down the boundaries between fundamental and clinical approaches.

More detail HERE

In the thoracic spinal cord, CSF-cNs are in the vicinity of sympathetic preganglionic neurons (SPNs, cholinergic neurons) which represent the main output from the sympathetic autonomous system to control and modulate autonomic functions and body homeostasis. SPNs activity is controlled by supraspinal projections, sensory feedback from the periphery and intraspinal neuronal circuits. The organization of this spinal network is poorly understood, as are the potential actors. Because of the proximity between CSF-cNs and SPNs and their potential role as sensors of metabolic and homeostatic activity, we hypothesize that CSF-cNs would represent synaptic partners of SPNs capable of integrating the information conveyed by the CSF and of modulating the SPN activity and the autonomous functions (Funding 2021, ANR SYMPA-CSFcneurons in collaboration with Sandrine Bertrand INCIA, Bordeaux).

The selected candidate will join SpiCCI as Technician/Research Assistant and will participate to the anatomical and cell biology part of the project under the direction of the team leader and its research engineer.

He/she will develop, validate, optimize, and implement viral infection strategies and neuronal tracing approaches for the project. He/she will be involved in the clarification and histology studies. In parallel, he/she will participate in the development and preparation of primary cultures of CSF-cNs and/or spinal cord organotypic slices to perform in vitro genetic manipulations. The candidate should be dynamic, committed and persevering as well as able to adapt quickly to his/her new environment.

Selection Procedures:

Send a CV with a cover letter presenting the professional background and justifying the reasons for joining SpiCCI + 2 recommendation letters to Nicolas Wanaverbecq (nicolas.wanaverbecq@univ-amu.fr). For more information contact NW. Deadline for application November 31st, 2021.