Job ID: 63297

Ph.D. student position in Neuroscience

Position: Ph.D. Student

Deadline: 10 December 2021

Employment Start Date: 1 January 2022

Contract Length: 3 years

City: Erlangen

Country: Germany

Institution: Friedrich-Alexander Universität Erlangen-Nürnberg

Department: Department of Psychiatry and Psychotherapy

Description:

Two PhD positions are available in the groups of Prof. Johannes Kornhuber on “Bioactive Sphingolipids in Psychiatric Diseases” and of PD Dr. Christiane Mühle working on “Biomarkers of Neuropsychiatric Diseases / Translational Psychiatry” at the Department of Psychiatry and Psychotherapy at the Universitätsklinikum Erlangen and the Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany.

The objective of our work is the identification and characterization of biomarkers, risk factors and underlying mechanisms of neuropsychiatric diseases with a focus on sphingolipids and sphingolipid metabolizing enzymes. Thereby, we aim to improve the understanding of the pathogenesis, prevention, diagnosis and personalized therapy. In our translational PhD projects, you will assess the utility of targets like the sphingomyelin synthase as biomarkers for depression and therapeutic response and study their regulation at different levels using biomaterial from several clinical studies. Cell culture models will also be used to understand mechanistic details. In collaboration, you will then validate the findings from patients and cell culture in mouse models of depression and test candidate targets for fast-acting antidepressants.

We are looking for curious and highly motivated students with an excellent Diploma/Master degree in Molecular Medicine, Biology, Biochemistry or related fields. Candidates should have a strong background in Neurobiology or Molecular Biology to work independently as well as in a team-oriented manner. We offer state-of-the-art facilities in a very collaborative environment and interdisciplinary team.

The doctoral researchers will be part of the DFG-Research Training Group 2162 “Neurodevelopment and CNS Vulnerability” at the FAU, which offers a 3-year structured, international PhD program in basic and translational neurobiology with mentorship, scientific and soft-skill training and support.

How to apply:

Please submit applications via email as a single file to grk2162@fau.de

(1) Letter of motivation

(2) Curriculum vitae

(3) Transcript of Records

(4) Summary of Research Experience and Master Project

(5) List of publications

(6) Two letters of reference

 

For further information, please visit our websites www.grk2162.med.fau.de/ and

www.psychiatrie.uk-erlangen.de/forschung/arbeitsgruppen/biomarkertranslationale-psychiatrie/