Job ID: 64444

Ph.D. student: GABAergic synapses and circuits in psychiatric disorders

Position: Ph.D. Student

Deadline: 31 January 2022

Employment Start Date: 1 May 2022

Contract Length: 3 years (with possibility of extension)

City: Mainz

Country: Germany

Institution: Mainz University Medical Center

Department: Institute of Microscopic Anatomy and Neurobiology

Description:

We are seeking a highly motivated PhD student to join us in studying the role of GABAergic inhibitory synapses and circuits in the pathophysiology and treatment of psychiatric disorders.

Research in our laboratory at the Institute of Microscopic Anatomy and Neurobiology of the Mainz University Medical Center focuses on the mechanisms by which GABAergic synapses and circuits, particularly in the amygdala, mediate behaviors related to anxiety disorders and autism spectrum disorders (https://www.unimedizin-mainz.de/iman/krueger-burg-lab/research.html?L=1). Using mouse models and a wide range of experimental approaches ranging from molecular studies through circuit level analyses to assessment of defensive and social behaviors, we aim to identify strategies that may ultimately lead to development of new therapeutic interventions.

To this end, we are looking for a new team member with a strong background in neuroscience and an interest in studying the neural circuits that mediate social dysfunction in psychiatric disorders. The ideal candidate will also have prior experience in the study of mouse behavior, as well as in the use of systems neuroscience approaches (including chemogenetics, optogenetics and/or in vivo Ca2+ imaging) to study behavioral circuits in mice. Given that the Institute of Microscopic Anatomy and Neurobiology is an international environment, strong English language skills are essential, and prior international experience is highly desirable.

We are offering a PhD position starting in April 2022 or later, fully funded by a three-year stipend from the Focus Program Translational Neurosciences (FTN) of the Johannes Gutenberg University Mainz (https://www.blogs.uni-mainz.de/ftn-eng/), a member of the Rhein-Main Neuroscience Network (http://www.rmn2.de/). The successful candidate will be enrolled in the Mainz Research School of Translational Biomedicine, through which the PhD degree will be obtained (https://www.unimedizin-mainz.de/transmed/phd-mdphd-in-translational-biomedicine.html).

Applications including a letter of motivation, CV, university transcripts, and contact information for two letters of recommendation, should be sent to Prof. Dilja Krueger-Burg (dkruegerburg@uni-mainz.de) by January 31, 2022.