Job ID: 80871

Scientific Associate – in vivo CNS neuropharmacology / neurobiology

Position: Scientific Associate

Deadline: 29 July 2022

Employment Start Date: 1 July 2022

Contract Length: Permanent

City: Basel

Country: Switzerland

Institution: Idorsia Pharmaceuticals

Department:

Description:

About Idorsia Pharmaceuticals Ltd

Idorsia Ltd is reaching out for more – We have more ideas, we see more opportunities and we want to help more patients.

In order to achieve this, we will develop Idorsia into one of Europe’s leading biopharmaceutical company, with a strong scientific core.

Headquartered in Switzerland – a European biotech hub – Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet – the ideal constellation to bringing R&D efforts to business success.

Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 600 highly qualified specialists dedicated to realizing our ambitious targets.

We are seeking a motivated Senior Scientific Associate for a permanent position in the CNS department starting as soon as possible.

Job Responsibilities

  • Plan and execute in-vivo pharmacological studies in rodent models of psychiatric and neurological diseases
  • Perform behavioral and neurological evaluations (e.g., motor function, cognition) in rats and mice
  • Sample biological fluids (cerebrospinal fluid, blood) and tissues (brain, spinal cord) and perform ex vivo analyses (e.g., ELISA, immunohistochemistry, microscopy)
  • Responsible for the accurate documentation of experiments in the electronic lab journal
  • Supervise the breeding of one or two transgenic mouse/rat colonies
  • Literature search for the setup of relevant experimental methods, selection of the most appropriate models and optimization of existing protocols
  • Writing of internal scientific reports, and veterinary animal licenses
  • Communicate research findings internally, and collaborate closely with other research groups in the company

Candidate Requirements

  • Bachelor’s or Master’s degree in Science (Biology/Pharmacology/Biochemistry), ideally with additional knowledge in Neuroscience; alternatively, a technical education with longer experience on the job; candidates holding a PhD will generally not be considered
  • Recognized as an animal experimenter (LTK1 or equivalent)
  • Practical work experience in the field of neuroscience for > 4 years in academia or, preferably, in an industrial setting
  • Hands-on experience in animal dosing (oral gavage, subcutaneous and intraperitoneal injections), and necropsy (e.g., microdissection of brain regions, muscles, and spinal cord)
  • Hands-on experience with complex behavioral and physiological tests in rodents; experience with operant testing and telemetry (e.g., for EEG/EMG assessment) is an asset
  • Hands-on experience in surgical techniques in rodents (experience in stereotaxic surgery is an advantage)
  • Experience with multifaceted analysis software for behavioral analysis (e.g., Ethovision, Any-Maze); experience with AI-based tools (e.g., DeepLabCut, DeepSqueak) and basic programming knowledge are an asset
  • Expertise in ex-vivo methods (e.g., histology, microscopy) is considered a plus
  • Ability to plan, methodologically perform, carefully analyze, accurately document experiments and present results
  • Enthusiasm, flexibility, and ability to work in an interdisciplinary environment
  • Availability to occasionally work on weekends if chronic studies are ongoing
  • Fluency in English (verbal and written)

What Idorsia offers

  • Exciting opportunities for development and professional growth within our dynamic organization
  • A collaborative and solution-oriented environment where you can make a difference
  • An innovative and open culture in a truly multicultural environment
  • A competitive salary and generous social benefits

Please apply directly on Idorsia website.

Scientific Associate – in vivo CNS neuropharmacology / neurobiology (idorsia.com)