Job ID: 81637

Research Fellow – Gene Therapy for Epilepsy

Position: Post-doctoral Position

Deadline: 30 May 2022

Contract Length: 2 years

City: London

Country: United Kingdom

Institution: UCL

Department: Clinical and Experimental Epilepsy


Research in the Experimental Epilepsy Group, based in the Department of Clinical and Experimental Epilepsy, spans across fundamental mechanisms of vesicle fusion and synaptic transmission, ion channel biology, experimental models of epilepsy, the function of neural circuits, and neurological diseases modelled in rodents and flies.

We are now recruiting a Research Fellow to design, optimise, and validate an innovative gene therapy tool to treat Dravet syndrome, with translational potential. Under the supervision of Dr Gabriele Lignani you will use techniques including electrophysiology, molecular biology, in vivo electrophysiology, and behaviour.

The Institute offers 41 days of annual leave (inclusive of bank holidays and college closure dates), a generous pension scheme, access to UCL’s community benefits including lunch-hour lectures, exhibitions, and museums, as well as an extensive range of staff benefits.

The post is available from July – September 2022 and is funded by GOSH Charity and Sparks until 03 April 2024 in the first instance.

Key Requirements

You will have a PhD in Neuroscience or a related discipline, coupled with experience of in vitro or in vivo electrophysiology, molecular biology methods, and experience of working with rodents. You’ll be a great communicator, have good interpersonal skills, and strong problem-solving abilities. Experience with immunofluorescence and confocal microscopy, and rodent behaviour, would be very desirable.

Appointment at Grade 7 is dependent upon having been awarded a PhD; if this is not the case, initial appointment will be at Research Assistant Grade 6B (salary £32,217 – £33,958 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.

Further Details

A job description and full person specification can be accessed below.

To apply for the vacancy, please click here:

For informal enquiries about the role please contact Dr Gabriele Lignani (

If you have any queries regarding the application process, please contact the Institute of Neurology HR Team (