Job ID: 85915

Postdoctoral fellow or research associate/ingineer in motor neurobiology and transcriptomic profiling

Position: Post-doctoral Position

Deadline: 31 August 2022

Employment Start Date: 1 October 2022

Contract Length: 1 year with the possibilty for extension

City: Saclay

Country: France

Institution: CNRS

Department: Paris-Saclay Institute of Neuroscience

Description:

A fully-funded position is available to work on the neuronal control of movements, with a focus on brainstem and spinal cord circuits for locomotion and body movements. With the support of ANR and FRM grants, you will in particular investigate the diversity of specific brainstem and spinal neuronal neurons from the connectomics and gene expression standpoints, combining mouse genetics, viral synaptic tracings, high-throughput single-nucleus profiling and anatomical reconstructions.

The contract is for at least one full year, with a possibility for extension.

You will be joining a dynamic team of neurophysiologists with recognized expertise in deciphering the organization of motor circuits using multiple anatomical, genetic and functional approaches. You will have access to state-of-the-art viral tools, transgenic mice lines, and core facilities for sequencing and imaging.

You will evolve in the stimulating and international environment of the NeuroPSI institute, dedicated to studying brain function from genes to artificial intelligence. Our lab just moved to a brand-new building at the heart of the multi-disciplinary scientific park of Paris-Saclay, 20 Km south of Paris.

The ideal candidate holds a PhD, should be interested in brainstem and spinal motor circuits and has some of the following qualifications:

  • Molecular biology including tissue dissociation and FACS sorting;
  • RNA sequencing and genomic data analysis ideally at the single cell or single nucleus level;
  • Immunohistochemistry and in situ hybridization;
  • Be genuinely motivated, have excellent communication skills, and be sensible to a healthy and constructive team-spirit.
  • Minimal computer literacy, including Seurat, Matlab, R, or python will be a valuable asset;
  • Interest in learning experimental approaches on transgenic mice including surgical procedures and viral tools.

Interested candidates should send to Julien Bouvier:

  • a 2-page statement of interest, summarizing your past work and interest in our team and projects;
  • a CV including your education, technical skills, previous funding, and publication list if applicable (for the postdoctoral position);
  • at least 2 references.