Job ID: 106927

Postdoctoral Positions in System Neuroscience & Proteomics of Sleep

Position: Post-doctoral Position

Deadline: 1 March 2024

Employment Start Date: 1 April 2023

Contract Length: Yearly renewable

City: Bern

Country: Switzerland

Institution: University of Bern (Switzerland)

Department: Zentrum fur Experimentelle Neurologie (ZEN), Dept of Neurology (Bern)

Description:

2 Postdoctoral Positions in System Neuroscience & Proteomics of Sleep

 

The laboratory of Prof. Antoine Adamantidis in the Department of Neurology at the University of Bern and Prof. Maria Robles, Systems Chronobiology, Faculty of Medicine, LMU Munich are seeking for highly motivated postdoctoral fellows to work in the field of sleep neurophysiology and MS-based proteomics/systems biology. The project is funded by the SNF and aims at identifying molecular markers of brain activity during sleep associated with neural dynamics and plasticity of thalamo-cortical circuits (see Nature 2007; Nat. Neurosci. 2013, 2016, 2018; and Science 2016, 2022, doi:10.1126/science.aav2642; doi:10.1126/science.aav3617).

The Tidis Lab is located in the Zentrum für Experimentelle Neurologie (ZEN) from the Department of Neurology, University of Bern at the Inselspital University Hospital, Switzerland. The ZEN is a research center developing a unique translational environment supported by strong interactions between clinical and experimental laboratories with a long expertise in sleep, epilepsy and stroke.

The Robles Lab is located in the Institute of Medical Psychology and the Biomedical Center of the Ludwig Maximilian University of Munich (LMU), a multidisciplinary scientific and international environment with strong circadian and sleep research focus and proteomics technology.  LMU is a leading research university in Europe founded in 1472 and committed to the highest international standards of excellence in research and teaching.

To further strengthen our collaborative groups, we are looking for two candidates with a recent doctoral degree (PhD) in 1) neuroscience, neuro-engineering, or 2) biochemistry, proteomics, bioinformatics, systems biology; and evidence of publication history in any of those fields.  Applicants with previous experience in 1) molecular neurosciences, rodent stereotaxic surgery, optogenetics, in vitro/vivo electrophysiology, in vivo calcium imaging (miniscope, LS2PM) or behavioral analysis (e.g., sleep, instrumental learning, reward, fear learning, etc.) or 2) single cell proteomics, DIA methods and computational skills are a strong asset. Experience with 1) signals analysis (calcium imaging) and computer programming (Matlab, Spike, C++,…) and 2) high-throughput quantitative proteomics methodologies, operation of nanoLC-HPLC and Thermo Orbitrap instruments and proteomics data analysis programming are required. Excellent written and oral communication skills, ability to work independently and together with a research team, and aptitude to mentor undergraduate and graduate students are also necessary attributes.

Both labs offer solid scientific and technical expertise in system and molecular neurosciences, respectively, together with a highly collaborative environment.

To apply: Please send your application (CV, letter describing your scientific interests, contact of three references) by email to Prof. Antoine Adamantidis (flurina.kempf@insel.ch) or Prof. Maria Robles (crobles@med.lmu.de). Screening of applications will begin immediately and the position will remain open until filled. Only selected applicants will be contacted for interview.