Job ID: 113917
Intracellular signaling pathways activated by a novel optoogenetic tool
Position: Post-doctoral Position
Deadline: 30 September 2023
Employment Start Date: 1 October 2023
Contract Length: at least 1 year
City: Paris
Country: France
Institution: INSERM
Department: Institut du Fer a Moulin
Description:
This project is within the framework of an European JPND project, in the team of Jean-Antoine Girault (Institut du Fer à Moulin, Inserm & Sorbonne University U1270) in collaboration with Louise-Laure Mariani (ICM, Paris Brain Institute).
The project is to characterize intracellular signaling pathways activated in striatal neurons by a novel nanoparticle-based optogenetic tool sensitive to infrared light. Experiments will include biosensor imaging using confocal and 2-photon microscopy in neuronal cell cultures and striatal slices.
The candidate is expected to have previous experience in neuronal cell culture and live cell imaging.