Job ID: 113917

Intracellular signaling pathways activated by a novel optoogenetic tool

Position: Post-doctoral Position

Deadline: 30 September 2023

Employment Start Date: 1 October 2023

Contract Length: at least 1 year

City: Paris

Country: France

Institution: INSERM

Department: Institut du Fer a Moulin

Description:

This project is within the framework of an European JPND project, in the team of Jean-Antoine Girault (Institut du Fer à Moulin, Inserm & Sorbonne University U1270) in collaboration with Louise-Laure Mariani (ICM, Paris Brain Institute).

The project is to characterize intracellular signaling pathways activated in striatal neurons by a novel nanoparticle-based optogenetic tool sensitive to infrared light. Experiments will include biosensor imaging using confocal and 2-photon microscopy in neuronal cell cultures and striatal slices.

The candidate is expected to have previous experience in neuronal cell culture and live cell imaging.