Job ID: 116985
PhD student position in Neuron-glia interactions and extracellular matrix post-stroke
Position: Ph.D. Student
Deadline: 10 December 2023
Employment Start Date: 1 February 2024
Contract Length: 2-3 years with possibilty of extension
City: Essen
Country: Germany
Institution: University Hospital Essen
Department: Neurology
Description:
The PhD position is available in the Research group “Neuron-glia interactions and extracellular matrix post-stroke” at the Neurology Department of University Hospital Essen. We previously demonstrated that the remodeling of the extracellular matrix (ECM) by microglia and astrocytes plays a critical role in post-stroke neuroplasticity and recovery, representing a promising yet underexplored target for stroke therapies. Now, we are developing innovative translational treatments that promote brain plasticity and recovery after stroke by modulating ECM remodeling and ECM-glia interactions.
The new colleague will benefit from a highly collaborative international environment, cutting-edge equipment, local tuition programs, and ample networking possibilities. Depending on interest and starting skills, the applicant will be offered to join the in vivo or the in vitro team. The successful applicant should be:
- Strongly interested in neuron-glia interactions, brain ECM, and stroke recovery;
- Academically trained in Biology/Biomedicine/Biophysics/Neuroscience or related field;
- Fluent in English written and spoken;
- Skilled in at least 2 of the following experimental techniques*:
| Team in vitro | Team in vivo |
| – Mammalian cell culture
– hiPSC culture – ICH and fluorescent microscopy – Live-cell imaging – Patch-clamp electrophysiology – MEA electrophysiology |
– Ischemic stroke models in mice/rats
– Mouse genetic models – IHH and fluorescent microscopy – Calcium imaging – Superresolution STED/SIM/STORM microscopy |
Application letters describing your background, CV, and contacts of two potential referees should be submitted by email to:
Dr. Egor Dzyubenko
E-mail: egor.dzyubenko@uk-essen.de
Department of Neurology and Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Hospital Essen, Hufelandstraße 55, 45122 Essen
* Multiclassing scientists are very welcome