Job ID: 117788

Two Postdoc positions in molecular and behavioral neuroscience

Position: Post-doctoral Position

Deadline: 31 August 2024

Employment Start Date: 1 March 2024

Contract Length: 2 years

City: Linkoping

Country: Sweden

Institution: Linkoping University

Department: BKV

Description:

Job description

We are looking to appoint TWO Postdoctoral fellows in Experimental Psychiatry. The successful candidatess will work in the Estelle Barbier OR Ida Fredriksson group at the Center for Social and Affective Neuroscience (CSAN) and department of Biomedicine and clinical research (BKV) https://liu.se/forskning/csan/forskargrupper. The lab offers all commodities for state-of -the-art molecular biology and behavioral research. We offer an international, young research environment with regular seminars and invited guest speakers. The candidate will work closely with other lab members at CSAN and supervise students.

Your tasks

The successful candidate will lead one of two projects that span from brain circuitry to transcriptomic analyses:

  1. Investigating the neural mechanisms underlying fear responses acquired through observation, known as vicarious or observational fear (PI Estelle Barbier)
  2. Studying the behavioral and neurobiological mechanisms of drug relapse and craving using animal models (PI Ida Fredriksson).

The main tasks in both project are:

– Performing behavioral testing

– Design and performance of studies to assess the functional role of candidate brain circuits in observational fear (optogenetic, viral vector, and chemogenetic DREADD-based approache)

– Performing molecular and biochemical techniques and analyses

– Transcriptomic analysis

 

Additional skills and experience (optional)

Skills/Qualifications for project 1:

We are seeking an individual with multidisciplinary expertise, particularly in molecular and behavioral aspects, including knowledge of brain circuits and animal models of anxiety.

The ideal candidate should meet the following criteria:

– PhD in cell biology, molecular biology, or related field

– Excellent skills in basic molecular biology and biochemical techniques, including immunoblotting, (q)PCR, (co-)immunoprecipitation, microscopy and epigenetics

– Very good written and spoken English language skills

– Working experience with tissue processing and handling

– Excellent skills in rat behaviors testing (fear conditioning)

– Independent thinking and proactive

Additional desirable skills for project 1:

– Working experience with high-throughput assays such as RNA sequencing is a bonus

– An additional asset would be proficiency in bioinformatics skills (Deeplabcut, sequencing analysis)

– Ability to work in a team, excellent interpersonal skills.

Skills/Qualifications for project 2:

– PhD in behavioral neuroscience, experimental psychiatry, or a related discipline

– Excellent skills working with rat models for addiction or related discipline.

– Excellent skills in basic molecular and biochemical techniques such as PCR, immunohistochemistry, RNAscope

– Experience working with confocal and fluorescence microscopy, microscopic imaging, and signal quantification.

– Very good written and spoken English

– Ability to work in a team, excellent interpersonal skills

Additional desirable skills for project 2:

– Proficient in intravenous catheterization surgery

– Experience in behavioral neuroscience and stereotaxic surgery

– Experience with high-throughput assays such as RNA sequencing is a bonus

Please supply us with:

  • Motivated application
  • Curriculum Vitae, including publication list
  • References/recommendations

If you have any questions, feel free to contact estelle.barbier@liu.se (Project 1) ida.fredriksson@liu.se (Project 2)