Job ID: 119009

PhD position in molecular neuroscience

Position: Ph.D. Student

Deadline: 4 June 2024

City: Frankfurt am Main

Country: Germany

Institution: Goethe University Frankfurt

Department: Institute of Clinical Neuroanatomy


The Institute of Clinical Neuroanatomy of Goethe University Frankfurt invites applications for the following position of a Research Assistant/ PhD student (m/f/d) (E 13 TV-G-U, 65% part time):

The position is for three years with the possibility of extending and is expected to start at the earliest possible date. The salary grade is based on the job characteristics of the collective agreement (TV-G-U) applicable to Goethe University.

We are studying how synaptic activity drives long-lasting molecular and cellular adaptations of neurons with a particular focus on mitochondrial function and neuronal bioenergetics ( We are interested in the molecular mechanisms that mediate these adaptations and how metabolic plasticity and mitochondria are affected during brain aging and neuroinflammatory diseases. To address these questions, we use a broad range of state-of-the-art methods that include biochemical and molecular assays, viral gene transfer, spatial gene expression profiling, and multiparametric live imaging of genetically encoded and chemical reporters in slice cultures. The position offers the opportunity for further qualification (doctorate). Goethe University accompanies the doctoral phase with a structured academic and professional development program (

Your responsibilities:

  • continuing scientific and didactic education
  • participation in research projects on neuronal plasticity and homeostasis
  • participation in undergraduate teaching (Master program in interdisciplinary neuroscience)

Your qualifications:

  • completed scientific university studies in biology, biochemistry, human medicine or a related subject
  • practical experience or basic knowledge in one of the fields of molecular cell biology, bioenergetics, live cell microscopy, mouse models is desirable
  • willingness to get involved in research projects of the institute, and to learn and apply necessary techniques
  • ability to plan and carry out experiments independently
  • excellent English language skills and a high degree of independence, flexibility and motivation

Please submit your application including a cover letter explaining your previous work and your motivation to this position, a CV, academic certificates, and contact details of two academic referees in a single PDF file by 04.06.2024 to: Prof. Carlos Bas Orth, Neuroscience Center, Haus 89, Goethe-Universitaet, Theodor-Stern-Kai 7, 60590 Frankfurt am Main. (E-mail: