Job ID: 121836

Post-doc in Neuroscience – Lyon – France

Position: Post-doctoral Position

Deadline: 28 February 2025

Employment Start Date: 1 April 2025

Contract Length: 24 months

City: Bron

Country: France

Institution: Université Claude Bernard Lyon 1

Department: Centre de Recherche en Neurosciences de Lyon

Description:

Experience: 0-1 year post-PhD

Starting date: April 1st 2025         Working time: full time

Salary: 2320 euros (before tax) per month

 

Missions

This position is proposed within the framework of a project funded by Université Claude Bernard Lyon 1 (AAP SENS 2024). The aim of this project is to better understand the consequences of aging on brain function and the sex-associated specificities, as well as the underlying cellular mechanisms in the mouse model. This project is also developing a remediation component, with the use of odors to modulate brain function.

 

Activities

Under the supervision of the PI, the post-doctoral fellow will be in charge of developing and conducting the scientific project. The post-doctoral fellow will plan and carry out experiments including behavioral approaches, synaptic connectivity analysis (mGRASP technology) and intracerebral fiber photometry recordings in mice. He/she will collect and analyze data and actively participate in the interpretation of results. The candidate is also expected to monitor the literature and technical developments related to the research project, discuss and present his/her data to the team and at national or international conferences, and promote his/her work in the form of scientific publication(s).

Some of the necessary methodologies are already available within the team, and the post-doc will interact closely with team members to implement them. The candidate will be expected to work autonomously, and will be able to develop the tools required for the project from those already available within the team.

 

Expected Skills

A PhD in neuroscience is required, and a certificate for animal experimentation (equivalent to French level 1 – conception) and surgery. The skills needed for this position are to:

– master the conduct of integrative neuroscience experiments in mice

– master one or several cellular imagery techniques (fiber photometry, calcium imaging, confocal microscopy, bi-photon…) and the methods and software necessary for the analysis of associated signal

– know how to use a programming language (Matlab, Python, R…)

– master statistical analysis tools (R in particular)

– have good writing and communication skills

– have a good level of English

– have a good ability to work in a team and also autonomously

– know how to organize your working time efficiently

 

Work context – The candidate will work in the Neuropop team (https://www.crnl.fr/fr/equipe/neuropop) of the Lyon Neuroscience Research Center CRNL (at the Vinatier hospital in Bron, Neurocampus building). The CRNL (https://www.crnl.fr/) is a multi-thematic and dynamic research unit in Lyon (University Claude Bernard Lyon 1 – CNRS – INSERM), with more than 450 members (including researchers, university professors, post-doc, PhD students and technical and administrative staff). The research themes of the Neuropop team focus on the plasticity of olfaction in rodent and human models, and its dysfunction in various pathological contexts (aging, stress, dysosmia, etc). The team is composed of 13 people (3 CNRS researchers, 3 university professors, 4 PhD students and 3 post-docs) and is supported by shared technical staff (1 engineer in signal analysis, 2 technicians in Biology). The team regularly trains undergraduate students and Master interns. Within the current project, the team benefits from the technical platforms of the CRNL and UCBL (animal facility, microscopy CIQLE https://ciqle.univ-lyon1.fr/, GenCyti https://www.crnl.fr/fr/plateforme/gencyti).

Lyon is the capital of the Auvergne Rhone-Alpes region (south-east France), with easy and direct access to Paris (2 hours by train). Lyon is a dynamic university town in terms of cultural, musical and artistic events, and close to the mountains for outdoor enthusiasts.

 

Constraints and risks occasional weekend work, depending on the needs of animal experimentation.

 

Additional information – The application must include the following documents: a letter of motivation indicating in particular the research interests and the long-term objectives of the candidate; a curriculum vitae detailing the technical skills of the applicant and the main results obtained so far (published or not); and the contact details of a person with whom the candidate has worked and who could write a letter of recommendation.