Job ID: 122979

PhD position in molecular neuroscience: Extrinsic and intrinsic regulation of myelination in the central nervous system

Position: Ph.D. Student

Deadline: 25 August 2025

Employment Start Date: 1 September 2025

City: Erlangen

Country: Germany

Institution: Friedrich-Alexander-Universität Erlangen-Nürnberg

Department: Institut für Biochemie

Description:

PhD position in molecular neuroscience: Extrinsic and intrinsic regulation of myelination in the central nervous system

A PhD position is available in the group of Dr. Tim Aberle at the Institute of Biochemistry (Friedrich-Alexander University Erlangen-Nürnberg), starting September 2025.

Role summary

We are working on extrinsic and intrinsic regulation of the myelination process in the central nervous system, where defects in the development of oligodendrocytes, the myelin producing cell of the central nervous system, can lead to devastating diseases such as multiple sclerosis or epilepsy. This project will analyze the role of G-protein coupled receptors and extrinsic and intrinsic calcium signals during myelination using histological, molecular biology, biochemical, and high throughput sequencing techniques. Additionally, many analyses involve the use of primary cell culture, organotypic brain cultures, or transgenic/knockout mouse models.

Requirements

We are looking for an interested and motivated candidate with an excellent master’s degree in life sciences, biochemistry, biology, molecular medicine, molecular neuroscience, or equivalent fields of study. Fluent oral and written English language skills are required (minimum CEFR level: B2).

Experience in neurosciences and practical experience in standard molecular biology, cell culture, and histology techniques are desired.

What we offer

The 65% position is paid according to the TV-L E13 tariff. We offer qualified training and comprehensive scientific supervision within a highly collaborative team. This position is available through the Research Training Group of the Interdisciplinary Center for Clinical Research (IZKF) Erlangen and the applicant will be integrated accordingly. The applicant will have the opportunity to educate themselves on a professional and personal level and will be able to network with other PhD students and established researchers within the neuroscience community. Mentoring and soft skill seminars are offered and part of the structured PhD program. For further information please visit the web page of the IZKF: https://www.izkf.med.fau.de/en/nachwuchs/izkf-doktorandenakademie/#collapse_0

How to apply:

Please submit the following documents as a single PDF file (maximum size 10 MB) to tim.aberle@fau.de:

  • Letter of motivation including a short summary of research experience and the master’s project
  • Curriculum vitae
  • Transcript of records or educational certificates
  • List of publications (if applicable)
  • Contact information for two references (name, relation to candidate, e-mail, postal address, and telephone number)