Hans Vanbokhoven
CountryNetherlands
Society affiliation European Molecular and Cellular Cognition Society (EMCCS)
Position Principal Investigator/Group Leader
University/Organisation Radboudumc
Domain Neurogenesis and Development
Sub domains Intellectual disability
Lab description
My group investigates the genetic, molecular and cellular underpinnings of rare neurodevelopmental disorders involving intellectual disability, ASD, epilepsy and neural migration defects. This has led to the identification of >100 genes carrying rare causitive variants for such disorders. This genetic knowledge is used as a starting point for fundamental research aimed to gain insight into the insights neurobiological mechanisms of disease and develop new opportunities for therapeutics. To do so, he has incorporated powerful in vitro and in vivo models in his research group, including the fruit fly and human IPSC-derived neural cell models.
Lab URLhttps://www.radboudumc.nl/en/people/hans-van-bokhoven