Marloes Henckens

CountryNetherlands

Society affiliation Dutch Neurofederation

Position Principal Investigator/Group Leader

University/Organisation Donders Institute for Brain, Cognition and Behaviour, Radboudumc

Domain Motivation, Emotion and Behaviour

Sub domains Animal models Anxiety and Fear-based Disorders Fear and adversive learning and memory

Lab description

We aim to understand the neural basis of stress resilience, and the factors that are predictive thereof, as this may hold the key to both the development of improved treatment and the prevention of stress-related disorders. Our lab studies resilience using animal models that allow for the controlled study of its molecular, cellular and neural circuit level underpinnings , differentiating individuals that are behaviorally resilient or susceptible to stress exposure. Our research has a strong translational character, both applying backtranslation of patient findings (eg, phenotypic heterogeneity), and using readouts that can be directly translated to the patient (eg, whole brain mapping of neuronal activity).