CAJAL Course: Advanced Techniques for Synapse Biology 2017

Bordeaux Neurocampus, FR

Attendance type(s): In Person

Event Dates: 03—23 Jul 2017

Synapses are the major sites of information processing in the brain. The complexity of the synapse has been described in the past few years in great molecular details and major achievements have been gained in the understanding of networks of proteins occurring at the pre-synaptic cytomatrix and the postsynaptic compartment of both excitatory and inhibitory synapses. Synaptic dysfunction is a central aspect of many brain disorders (“synaptopathies”) and synapses are and potentially will be the main target of drugs for brain diseases. Synapses integrate complex signals through temporal and spatial codes and undergo rapid structural and functional changes (synaptic plasticity) that underlie the formation of engrams in the brain. Maladaptation of such processes can lead to aberrant perception, cognitive dysfunction or neurodegeneration. The study of the molecular mechanisms of synaptic function and -plasticity are the key to understanding of how the brain works and what goes wrong in brain disease.
The advanced course will expose students to state-of-art techniques for molecular imaging and functional methodologies, through direct hands-on experiments.

Contact Details

Email: cajal@fens.org